Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.76 |
| ▸ | GAA | P10253 | 4/20 | 0.72 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CFTR | P13569 | 2/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8902306 | 0.92 | GAA (0.67) | KDM4EGAAPOLBALDH1A1HSD17B10 | |
| SCHEMBL29424850 | 0.90 | GAA (0.74) | KDM4EGAAPOLBALDH1A1HSD17B10 | |
| SCHEMBL6473999 | 0.90 | GAA (0.74) | KDM4EGAAPOLBALDH1A1HSD17B10 | |
| SCHEMBL31305136 | 0.90 | KDM4E (0.72) | KDM4EGAAPOLBALDH1A1HSD17B10 | |
| SCHEMBL2900351 | 0.89 | KDM4E (0.82) | KDM4EGAAPOLBALDH1A1HSD17B10 | |
| SCHEMBL6582728 | 0.88 | KDM4E (0.67) | KDM4EGAAPOLBALDH1A1HSD17B10 | |
| SCHEMBL31408659 | 0.86 | KDM4E (1.00) | KDM4EGAAPOLBALDH1A1HSD17B10 | |
| SCHEMBL372600 | 0.86 | KDM4E (1.00) | KDM4EGAAPOLBALDH1A1HSD17B10 | |
| SCHEMBL15797275 | 0.85 | KDM4E (0.66) | KDM4EGAAPOLBALDH1A1HSD17B10 | |
| SCHEMBL31738319 | 0.85 | KDM4E (0.71) | KDM4EGAAPOLBALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002231-A1 | 1-N-aryl-1,4-dihydropyridines, process for their preparation and their pharmaceutical application | BAYER AG (DE) | 1979-06-13 | — | — | EP | disclosed |