Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22795985 | 0.74 | KMT2A (0.38) | KMT2AMEN1PABPC1ADRA2CMAPK1 | |
| SCHEMBL82278 | 0.72 | — | — | |
| SCHEMBL8345081 | 0.72 | — | — | |
| SCHEMBL12648597 | 0.72 | — | — | |
| SCHEMBL12648729 | 0.72 | — | — | |
| SCHEMBL20200119 | 0.72 | — | — | |
| SCHEMBL2742276 | 0.71 | KMT2A (0.65) | KMT2AMEN1PABPC1ADRA2CGAA | |
| SCHEMBL15337804 | 0.71 | KMT2A (0.65) | KMT2AMEN1PABPC1ADRA2CGAA | |
| SCHEMBL8297563 | 0.71 | KMT2A (0.39) | KMT2AMEN1PABPC1ADRA2C | |
| SCHEMBL8002168 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618951-A | REACTING A CHLORODIFLUOROACETATE WITH A HALOSILANE USING AN UREA SILVENT AND A REDUCING AGENT | ELI LILLY AND COMPANY (US) | 1997-04-08 | — | — | US | claimed |
| US-5618951-A | REACTING A CHLORODIFLUOROACETATE WITH A HALOSILANE USING AN UREA SILVENT AND A REDUCING AGENT | ELI LILLY AND COMPANY (US) | 1997-04-08 | — | — | US | disclosed |