SCHEMBL2742276

SCHEMBL2742276

CC1C(C)N(C)C(=O)N1C

nearest known ligand 0.65

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.65
MEN1 O00255 2/20 0.65
PABPC1 P11940 1/20 0.65
ADRA2C P18825 1/20 0.59
TSHR P16473 1/20 0.42
GAA P10253 2/20 0.40
MAPK1 P28482 1/20 0.38
TP53 P04637 2/20 0.33
KDM4E B2RXH2 2/20 0.30
HSD17B10 Q99714 1/20 0.30
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15337804 1.00 KMT2A (0.65) KMT2AMEN1PABPC1ADRA2CTSHR
SCHEMBL14600741 0.82 KMT2A (0.54) KMT2AMEN1PABPC1ADRA2CTSHR
SCHEMBL22222120 0.80 KMT2A (0.46) KMT2AMEN1PABPC1ADRA2CTSHR
SCHEMBL28911345 0.76 ADRA2C (0.56) KMT2AMEN1PABPC1ADRA2CTSHR
Mebicar SCHEMBL1465373 0.74 ADRA2C (1.00) KMT2AMEN1PABPC1ADRA2CTSHR
Mebicar SCHEMBL15685069 0.74 ADRA2C (1.00) KMT2AMEN1PABPC1ADRA2CTSHR
SCHEMBL21414055 0.74 KMT2A (0.46) KMT2AMEN1PABPC1ADRA2CTSHR
SCHEMBL14924207 0.72 KMT2A (0.44) KMT2AMEN1PABPC1ADRA2CTSHR
SCHEMBL8902606 0.71 KMT2A (0.57) KMT2AMEN1PABPC1ADRA2CTSHR
SCHEMBL12667575 0.71 MEN1 (0.39) KMT2AMEN1PABPC1ADRA2CTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5618951-A REACTING A CHLORODIFLUOROACETATE WITH A HALOSILANE USING AN UREA SILVENT AND A REDUCING AGENT ELI LILLY AND COMPANY (US) 1997-04-08 US claimed
CN-112292198-B Composite hollow fiber membrane, method for producing same, hollow fiber membrane cartridge comprising same, and fuel cell membrane humidifier 可隆工业株式会社 2023-04-04 CN disclosed
US-10429753-B2 Electrophotographic photoconductor, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2019-10-01 US disclosed
US-20170312363-A1 MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2017-11-02 US disclosed
US-9760030-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2017-09-12 US disclosed
US-20170102627-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2017-04-13 US disclosed
US-9599917-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2017-03-21 US disclosed
US-RE45994-E1 Electrolytic capacitor and its manufacturing method PANASONIC CORPORATION (JP) 2016-05-03 US disclosed
EP-0938108-B1 Electrolytic capacitor and its manufacturing method PANASONIC CORP (JP) 2015-04-08 EP disclosed
US-8962233-B2 Actinic-ray—or radiation-sensitive resin composition and method of forming pattern using the composition FUJIFILM CORPORATION (JP) 2015-02-24 US disclosed
EP-0938108-A2 Electrolytic capacitor and its manufacturing method MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1999-08-25 EP disclosed
US-5618951-A REACTING A CHLORODIFLUOROACETATE WITH A HALOSILANE USING AN UREA SILVENT AND A REDUCING AGENT ELI LILLY AND COMPANY (US) 1997-04-08 US disclosed
EP-0299164-B2 PROCESS FOR THE PREPARATION OF 2,2-PARACYCLOPHANE UNION CARBIDE CORPORATION (US) 1993-04-21 EP disclosed
EP-0291889-B1 Process for the preparation of dichloro-[2,2] paracyclophane UNION CARBIDE CORPORATION (US) 1992-09-02 EP disclosed
US-5110903-A Films, coatings for electronic applications UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1992-05-05 US disclosed
EP-0299164-B1 PROCESS FOR THE PREPARATION OF 2,2-PARACYCLOPHANE UNION CARBIDE CORPORATION (US) 1990-09-19 EP disclosed
US-4849559-A HOFMANN ELIMINATION OF 2/3)-CHLORO-P-METHYL-BENZYLTRIMETHYLAMMONIUM HYDROXIDE UNION CARBIDE CORPORATION (US) 1989-07-18 US disclosed
EP-0299164-A1 Process for the preparation of 2,2-paracyclophane UNION CARBIDE CORPORATION (US) 1989-01-18 EP disclosed
EP-0291889-A1 Process for the preparation of dichloro-[2,2] paracyclophane UNION CARBIDE CORPORATION (US) 1988-11-23 EP disclosed
US-4769505-A Process for the preparation of the parylene dimer UNION CARBIDE CORPORATION (US) 1988-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170312363-A1 MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR HDGF, F11, F12 KMT2A 3974/4885MEN1 1056/4885PABPC1 2029/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.