Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 16/20 | 0.72 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8903211 | 1.00 | CCKBR (0.72) | CCKBRNPY1RTP53 | |
| SCHEMBL8903288 | 0.91 | CCKBR (0.66) | CCKBR | |
| SCHEMBL8904790 | 0.90 | CCKBR (0.73) | CCKBRNPY1R | |
| SCHEMBL8904366 | 0.87 | CCKBR (0.68) | CCKBR | |
| SCHEMBL9435303 | 0.87 | CCKBR (0.68) | CCKBR | |
| SCHEMBL8903724 | 0.86 | CCKBR (0.71) | CCKBR | |
| SCHEMBL7467452 | 0.83 | CCKBR (0.71) | CCKBR | |
| SCHEMBL8905038 | 0.82 | CCKBR (0.57) | CCKBRTP53 | |
| SCHEMBL8905032 | 0.82 | CCKBR (0.57) | CCKBRTP53 | |
| SCHEMBL8903122 | 0.82 | CCKBR (0.53) | CCKBRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618808-A | Benzothiazepine and benzoxazepine derivatives as cholecystokinin receptor antagonists | PFIZER, INC. (US) | 1997-04-08 | — | — | US | disclosed |
| EP-0648213-A1 | BENZOTHIAZEPINE AND BENZOXAZEPINE DERIVATIVES AS CHOLECYSTOKININ RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1995-04-19 | — | — | EP | disclosed |
| WO-1994001421-A1 | BENZOTHIAZEPINE AND BENZOXAZEPINE DERIVATIVES AS CHOLECYSTOKININ RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1994-01-20 | — | — | WO | disclosed |