Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 19/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8903311 | 1.00 | CCKBR (0.51) | CCKBR | |
| SCHEMBL8903106 | 0.92 | CCKBR (0.60) | CCKBR | |
| SCHEMBL8904296 | 0.92 | CCKBR (0.60) | CCKBR | |
| SCHEMBL8903101 | 0.92 | CCKBR (0.60) | CCKBR | |
| SCHEMBL8903044 | 0.90 | CCKBR (0.62) | CCKBR | |
| SCHEMBL8905718 | 0.90 | CCKBR (0.62) | CCKBR | |
| SCHEMBL8903048 | 0.90 | CCKBR (0.62) | CCKBR | |
| SCHEMBL8904274 | 0.85 | CCKBR (0.60) | CCKBR | |
| SCHEMBL9435384 | 0.85 | CCKBR (0.60) | CCKBR | |
| SCHEMBL8904459 | 0.81 | CCKBR (0.62) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618808-A | Benzothiazepine and benzoxazepine derivatives as cholecystokinin receptor antagonists | PFIZER, INC. (US) | 1997-04-08 | — | — | US | disclosed |
| EP-0648213-A1 | BENZOTHIAZEPINE AND BENZOXAZEPINE DERIVATIVES AS CHOLECYSTOKININ RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1995-04-19 | — | — | EP | disclosed |
| WO-1994001421-A1 | BENZOTHIAZEPINE AND BENZOXAZEPINE DERIVATIVES AS CHOLECYSTOKININ RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1994-01-20 | — | — | WO | disclosed |