SCHEMBL890318

SCHEMBL890318

C1C2CN12

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14536575 1.00
SCHEMBL15705647 0.76
Ammonia Solution, Strong SCHEMBL27167467 0.73
Fluoride Ion SCHEMBL436261 0.54
Fluoride Ion SCHEMBL27181984 0.44
Water SCHEMBL9763017 0.44
SCHEMBL27427293 0.38
SCHEMBL32663629 0.38
Fluoride Ion SCHEMBL23200840 0.27
Fluoride Ion SCHEMBL552564 0.27

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112204016-B Process for preparing fungicidally active triazole compounds UPL有限公司 2024-06-21 CN claimed
EP-0717042-B1 Process for preparing 1-(4,5-Dihydro-2-thiazolyle)-3-azetidine thiol derivatives WYETH LEDERLE JAPAN LTD (JP) 2001-05-23 EP claimed
US-5659043-A BACTERICIDES LEDERLE (JAPAN) LTD. (JP) 1997-08-19 US claimed
CN-122010956-A Chiral 1, 4-diazabicyclo [3.1.1] heptane derivatives, synthesis and application thereof 浙江师范大学 2026-05-12 CN disclosed
CN-122010956-A Chiral 1, 4-diazabicyclo [3.1.1] heptane derivatives, synthesis and application thereof 浙江师范大学 2026-05-12 CN disclosed
US-20250059217-A1 HETEROCYCLIC COMPOUNDS AND METHODS OF PREPARATION THEREOF BRIGHT MINDS BIOSCIENCES INC. (CA) 2025-02-20 US disclosed
EP-3604305-B1 NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVE OR SALT THEREOF WAKUNAGA PHARMA CO LTD (JP) 2024-08-28 EP disclosed
CN-112204016-B Process for preparing fungicidally active triazole compounds UPL有限公司 2024-06-21 CN disclosed
CN-117897376-A Heterocyclic compounds and process for preparing same 光明智慧生物科学公司 2024-04-16 CN disclosed
EP-4347561-A1 HETEROCYCLIC COMPOUNDS AND METHODS OF PREPARATION THEREOF Bright Minds Biosciences Inc. (CA) 2024-04-10 EP disclosed
US-11780834-B2 Solid forms of 3-((1R,3R)-1-(2,6-difluoro-4-((1-(3-fluoropropyl)azetidin-3- yl)amino)phenyl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)-2,2-difluoropropan-1-ol and processes for preparing fused tricyclic compounds comprising a substituted phenyl or pyridinyl moiety, including methods of their use GENENTECH, INC. (US) 2023-10-10 US disclosed
US-20040152759-A1 Combination administration of an indolinone with a chemotherapeutic agent for cell proliferation disorders SUGEN, INC. 2004-08-05 US disclosed
EP-1434774-A1 3-(4-SUBSTITUTED HETEROCYCLYL)-PYRROL-2-YLMETHYLIDENE)-2-INDOLINONE DERIVATIVES AS PROTEIN KINASE INHIBITORS Sugen, Inc. (US) 2004-07-07 EP disclosed
WO-2004045523-A2 COMBINATION ADMINISTRATION OF AN INDOLINONE WITH A CHEMOTHERAPEUTIC AGENT FOR CELL PROLIFERATION DISORDERS SUGEN, INC. (US) 2004-06-03 WO disclosed
US-6642232-B2 Antitumor agents SUGEN, INC. 2003-11-04 US disclosed
US-20030130235-A1 3-[4-Substituted heterocyclyl)-pyrrol-2-ylmethylidene]-2- indolinone derivatives as kinase inhibitors SUGEN, INC. 2003-07-10 US disclosed
US-20030130280-A1 Treatment of acute myeloid leukemia with indolinone compounds SUGEN, INC. 2003-07-10 US disclosed
WO-2003035009-A2 TREATMENT OF ACUTE MYELOID LEUKEMIA WITH INDOLINONE COMPOUNDS SUGEN, INC. (US) 2003-05-01 WO disclosed
WO-2003031438-A1 3-[4-(SUBSTITUTED HETEROCYCLYL)-PYRROL-2-YLMETHYLIDENE]-2-INDOLINONE DERIVATIVES AS KINASE INHIBITORS SUGEN, INC. (US) 2003-04-17 WO disclosed
US-5659043-A BACTERICIDES LEDERLE (JAPAN) LTD. (JP) 1997-08-19 US disclosed