Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | TLR4 | O00206 | 1/20 | 0.48 |
| ▸ | TLR2 | O60603 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MGMT | P16455 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25720536 | 0.90 | MGMT (0.49) | MAPTMAOBTLR4TLR2MAOA | |
| SCHEMBL4336283 | 0.88 | MAOB (0.51) | MAPTMAOBMAOANPC1RAB9A | |
| SCHEMBL1578214 | 0.85 | MGMT (0.50) | MAPTMAOBTLR4TLR2MAOA | |
| SCHEMBL1578345 | 0.85 | MAOB (0.49) | MAOBTLR4TLR2MAOACYP19A1 | |
| SCHEMBL4318351 | 0.85 | MAPT (0.51) | MAPTMAOBMAOAMEN1KMT2A | |
| SCHEMBL4318448 | 0.84 | MGMT (0.55) | MAOBMAOAMGMTGRM5 | |
| SCHEMBL4329304 | 0.84 | MAOB (0.54) | MAOBMAOAGRM5MRGPRX4 | |
| SCHEMBL1061802 | 0.82 | MAPT (0.56) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL29502955 | 0.82 | MAPT (0.56) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL1578371 | 0.81 | MAOB (0.52) | MAOBMAOAPTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120118068-A | Chemical process for preparing phenylpiperidinyl indole derivatives | 诺华股份有限公司 | 2025-06-10 | — | — | CN | disclosed |
| CN-112513025-B | Chemical process for preparing phenylpiperidinyl indole derivatives | 诺华股份有限公司 | 2025-03-25 | — | — | CN | disclosed |
| US-11578053-B2 | Chemical process for preparing phenylpiperidinyl indole derivatives | NOVARTIS AG (CH) | 2023-02-14 | — | — | US | disclosed |
| US-20220169630-A1 | CHEMICAL PROCESS FOR PREPARING PHENYLPIPERIDINYL INDOLE DERIVATIVES | NOVARTIS AG (CH) | 2022-06-02 | — | — | US | disclosed |
| US-11208398-B2 | Chemical process for preparing phenylpiperidinyl indole derivatives | NOVARTIS AG (CH) | 2021-12-28 | — | — | US | disclosed |
| EP-3823963-A2 | CHEMICAL PROCESS FOR PREPARING PHENYLPIPERIDINYL INDOLE DERIVATIVES | Novartis AG (CH) | 2021-05-26 | — | — | EP | disclosed |
| CN-112513025-A | Chemical process for the preparation of phenylpiperidinylindole derivatives | 诺华股份有限公司 | 2021-03-16 | — | — | CN | disclosed |
| WO-2020016749-A2 | CHEMICAL PROCESS FOR PREPARING PHENYLPIPERIDINYL INDOLE DERIVATIVES | NOVARTIS AG (CH) | 2020-01-23 | — | — | WO | disclosed |
| US-8492588-B2 | Benzyloxy anilide derivatives useful as potassium channel modulators | VALEANT PHARMACEUTICALS INTERNATIONAL (US) | 2013-07-23 | — | — | US | disclosed |
| US-20120329869-A1 | BENZYLOXY ANILIDE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | VALEANT PHARMACEUTICALS INTERNATIONAL | 2012-12-27 | — | — | US | disclosed |
| US-8188314-B2 | Benzyloxy anilide derivatives useful as potassium channel modulators | VALEANT PHARMACEUTICALS INTERNATIONAL (US) | 2012-05-29 | — | — | US | disclosed |
| US-20090326059-A1 | BENZYLOXY ANILIDE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | VALEANT PHARMACEUTICALS INTERNATIONAL (US) | 2009-12-31 | — | — | US | disclosed |
| US-4704401-A | HYPOTENSIVE AGENTS | RORER PHARMACEUTICAL CORPORATION (US) | 1987-11-03 | — | — | US | disclosed |
| US-4564640-A | Amidinoureas substituted in both the urea and amidino nitrogen positions | WILLIAM H. RORER, INC. (US) | 1986-01-14 | — | — | US | disclosed |
| US-4487779-A | HYPOTENSIVE AGENTS | WILLIAM H. RORER, INC. (US) | 1984-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220169630-A1 | CHEMICAL PROCESS FOR PREPARING PHENYLPIPERIDINYL INDOLE DERIVATIVES | IDO1, CYP3A7, PAH | MAPT 1921/4885MAOB 112/4885TLR4 2469/4885 |
| US-11208398-B2 | Chemical process for preparing phenylpiperidinyl indole derivatives | CYP3A7, CYP3A5, IDO1 | MAPT 1816/4885MAOB 129/4885TLR4 2132/4885 |
| US-20120329869-A1 | BENZYLOXY ANILIDE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | KCND2, KCNB2, KCNAB1 | MAPT 2021/4885MAOB 549/4885TLR4 3154/4885 |
| US-20090326059-A1 | BENZYLOXY ANILIDE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | KCND2, KCNB2, KCNAB1 | MAPT 2021/4885MAOB 549/4885TLR4 3154/4885 |
| US-11578053-B2 | Chemical process for preparing phenylpiperidinyl indole derivatives | IDO1, CYP3A7, PAH | MAPT 1921/4885MAOB 112/4885TLR4 2469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.