Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NOS3 | P29474 | 2/20 | 0.48 |
| ▸ | NOS1 | P29475 | 2/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1548295 | 1.00 | ALDH1A1 (0.57) | ALDH1A1KMT2AMAPTMEN1MAPK1 | |
| SCHEMBL1514547 | 0.81 | MAPT (0.61) | ALDH1A1KMT2AMAPTMEN1MAPK1 | |
| SCHEMBL1514546 | 0.81 | MAPT (0.61) | ALDH1A1KMT2AMAPTMEN1MAPK1 | |
| SCHEMBL12307304 | 0.81 | MAPT (0.49) | ALDH1A1KMT2AMAPTMEN1MAPK1 | |
| SCHEMBL6033210 | 0.80 | ALDH1A1 (0.63) | ALDH1A1KMT2AMAPTMEN1MAPK1 | |
| SCHEMBL20547552 | 0.80 | ALDH1A1 (0.63) | ALDH1A1KMT2AMAPTMEN1MAPK1 | |
| SCHEMBL21024214 | 0.79 | ALDH1A1 (0.92) | ALDH1A1KMT2AMAPTMEN1MAPK1 | |
| SCHEMBL2239365 | 0.79 | ALDH1A1 (0.92) | ALDH1A1KMT2AMAPTMEN1MAPK1 | |
| SCHEMBL21023910 | 0.79 | ALDH1A1 (0.92) | ALDH1A1KMT2AMAPTMEN1MAPK1 | |
| SCHEMBL90893 | 0.79 | ALDH1A1 (0.92) | ALDH1A1KMT2AMAPTMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110275070-A1 | HYBRIDIZATION AND MISMATCH DISCRIMINATION USING OLIGONUCLEOTIDES CONJUGATED TO MINOR GROOVE BINDERS | EPOCH PHARMACEUTICALS, INC. | 2011-11-10 | — | — | US | disclosed |