Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | RECQL | P46063 | 4/20 | 0.67 |
| ▸ | TOP1 | P11387 | 3/20 | 0.67 |
| ▸ | AURKA | O14965 | 3/20 | 0.67 |
| ▸ | CDC25B | P30305 | 3/20 | 0.67 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | P4HB | P07237 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | CASP1 | P29466 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Juglone SCHEMBL8908716 | 0.98 | MAPT (0.65) | MAPTALDH1A1KDM4ERECQLTOP1 | |
| Juglone SCHEMBL9280529 | 0.82 | MAPT (1.00) | MAPTALDH1A1KDM4ERECQLTOP1 | |
| Juglone SCHEMBL34185 | 0.82 | MAPT (1.00) | MAPTALDH1A1KDM4ERECQLTOP1 | |
| Juglone SCHEMBL29500185 | 0.82 | MAPT (1.00) | MAPTALDH1A1KDM4ERECQLTOP1 | |
| Juglone SCHEMBL17888856 | 0.80 | MAPT (0.96) | MAPTALDH1A1KDM4ERECQLTOP1 | |
| Juglone SCHEMBL9476381 | 0.79 | MAPT (0.85) | MAPTALDH1A1KDM4ERECQLTOP1 | |
| Juglone SCHEMBL14246054 | 0.78 | MAPT (0.92) | MAPTALDH1A1KDM4ERECQLTOP1 | |
| Juglone SCHEMBL25330089 | 0.77 | MAPT (0.81) | MAPTALDH1A1KDM4ERECQLTOP1 | |
| Juglone SCHEMBL2720570 | 0.75 | MAPT (0.85) | MAPTALDH1A1KDM4ERECQLTOP1 | |
| Anthraquinone SCHEMBL14245036 | 0.75 | MAPT (0.85) | MAPTALDH1A1KDM4ERECQLTOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5200513-A | Processes for producing doxorubicin, daunomycinone, and derivatives of doxorubicin | BOARD OF REGENTS, UNIVERSITY OF NEBRASKA-LINCOLN (US) | 1993-04-06 | — | — | US | claimed |
| US-5594158-A | Processes for producing doxorubicin, daunomycinone, and derivatives of doxorubicin | THE BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 1997-01-14 | — | — | US | disclosed |
| US-5200513-A | Processes for producing doxorubicin, daunomycinone, and derivatives of doxorubicin | BOARD OF REGENTS, UNIVERSITY OF NEBRASKA-LINCOLN (US) | 1993-04-06 | — | — | US | disclosed |