Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 3/20 | 0.42 |
| ▸ | KIF11 | P52732 | 4/20 | 0.41 |
| ▸ | AGXT | P21549 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 5/20 | 0.38 |
| ▸ | CTSK | P43235 | 5/20 | 0.38 |
| ▸ | CTSL | P07711 | 4/20 | 0.38 |
| ▸ | CTSB | P07858 | 2/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8903873 | 0.85 | PNMT (0.44) | CTSL | |
| SCHEMBL2090483 | 0.81 | AGXT (0.47) | CASRPTPN5KIF11AGXTHDAC4 | |
| SCHEMBL8903607 | 0.79 | PTPN5 (0.43) | CASRPTPN5KIF11HDAC4PSEN1 | |
| SCHEMBL8903499 | 0.76 | CASR (0.43) | CASRPTPN5KIF11AGXTHDAC4 | |
| SCHEMBL8903496 | 0.76 | CASR (0.43) | CASRPTPN5KIF11AGXTHDAC4 | |
| SCHEMBL18878437 | 0.76 | PTPN5 (0.66) | CASRPTPN5KIF11AGXTHDAC4 | |
| SCHEMBL23263973 | 0.75 | PNMT (0.46) | CASRPTPN5KIF11AGXTHDAC4 | |
| SCHEMBL8903402 | 0.73 | SLC13A5 (0.40) | PTPN5KIF11AGXTCTSSCTSK | |
| SCHEMBL3721175 | 0.73 | PTPN5 (0.51) | CASRPTPN5KIF11AGXTHDAC4 | |
| SCHEMBL2274626 | 0.73 | PTPN5 (0.69) | CASRPTPN5KIF11AGXTHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5627189-A | Insecticidal 5-substituted-2,4-diaminopyrimidine derivatives | FMC CORPORATION (US) | 1997-05-06 | — | — | US | disclosed |
| US-5587379-A | CONTROLLING INSECTS IN AGRICULTURAL CROPS | FMC CORPORATION (US) | 1996-12-24 | — | — | US | disclosed |
| US-5521192-A | TOBACCO BUDWORM, CABBAGE LOOPER, BEET ARMYWORM | FMC CORPORATION (US) | 1996-05-28 | — | — | US | disclosed |