Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 4/20 | 0.57 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.54 |
| ▸ | YARS1 | P54577 | 2/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.46 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CTSH | P09668 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL890404 | 1.00 | CTSC (0.57) | CTSCSLC7A5YARS1MMP2ERAP2 | |
| SCHEMBL8893265 | 0.94 | CTSC (0.67) | CTSCSLC7A5YARS1CYP1A2CYP3A4 | |
| SCHEMBL9293695 | 0.94 | CTSC (0.67) | CTSCSLC7A5YARS1CYP1A2CYP3A4 | |
| SCHEMBL9143188 | 0.94 | CTSC (0.67) | CTSCSLC7A5YARS1CYP1A2CYP3A4 | |
| SCHEMBL5996736 | 0.94 | CTSC (0.67) | CTSCSLC7A5YARS1CYP1A2CYP3A4 | |
| SCHEMBL516225 | 0.91 | CTSC (0.48) | CTSCSLC7A5YARS1MMP2CYP1A2 | |
| SCHEMBL27468879 | 0.91 | CTSC (0.48) | CTSCSLC7A5YARS1MMP2CYP1A2 | |
| SCHEMBL27650437 | 0.91 | SLC7A5 (0.51) | CTSCSLC7A5YARS1MMP2ERAP2 | |
| SCHEMBL11597695 | 0.89 | CTSC (0.49) | CTSCSLC7A5YARS1MMP2ERAP2 | |
| SCHEMBL2191632 | 0.88 | OPRD1 (0.61) | CTSCCYP1A2CYP3A4CTSHCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106456701-A | Modulation of complement activity | RA制药公司 | 2017-02-22 | — | — | CN | disclosed |
| US-20120083008-A1 | Methods for obtaining molecules with reduced immunogenicity | MARSHALL CHRISTOPHER P (US) | 2012-04-05 | — | — | US | disclosed |
| EP-1282722-B1 | STABILIZED PROTEINS | AVATAR MEDICAL L L C (US) | 2011-06-15 | — | — | EP | disclosed |
| US-7445912-B2 | Stabilized proteins | AVATAR MEDICAL LLC (US) | 2008-11-04 | — | — | US | disclosed |
| US-20070184518-A1 | Stabilized proteins | AVATAR MEDICAL LLC (US) | 2007-08-09 | — | — | US | disclosed |
| US-7037894-B2 | Stabilized proteins | AVATAR MEDICAL, LLC (US) | 2006-05-02 | — | — | US | disclosed |
| US-20050123530-A1 | Stabilized proteins | AVATAR MEDICAL, LLC (US) | 2005-06-09 | — | — | US | disclosed |
| US-20050054572-A1 | Methods for obtaining molecules with reduced immunogenicity | CALDER BIOSCIENCES INC. | 2005-03-10 | — | — | US | disclosed |
| EP-1282722-A4 | STABILIZED PROTEINS | AVATAR MEDICAL L L C (US) | 2004-04-07 | — | — | EP | disclosed |
| EP-1282722-A1 | STABILIZED PROTEINS | Avatar Medical, L.L.C. (US) | 2003-02-12 | — | — | EP | disclosed |
| US-20020061549-A1 | Stabilized proteins | CALDER BIOSCIENCES INC. | 2002-05-23 | — | — | US | disclosed |
| WO-2001029247-A1 | STABILIZED PROTEINS | AVATAR MEDICAL, LLC (US) | 2001-04-26 | — | — | WO | disclosed |