Aminocaproic Acid

Aminocaproic Acid

SCHEMBL8904221

CN(CCCCCC(=O)O)Cc1ccccc1.NCCCCCC(=O)O

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

PLATPLG

The experimentally established mechanism targets of Aminocaproic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLG known ✓ P00747 1/20 0.49
KDM4A O75164 2/20 0.67
KDM4C Q9H3R0 2/20 0.67
HTR7 P34969 4/20 0.57
CARM1 Q86X55 1/20 0.57
PRMT6 Q96LA8 1/20 0.57
PRMT8 Q9NR22 1/20 0.57
SIGMAR1 Q99720 2/20 0.56
APP P05067 3/20 0.53
KMT2A Q03164 3/20 0.51
ALDH1A1 P00352 2/20 0.51
GAA P10253 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.49
ACHE P22303 1/20 0.49
MAOB P27338 1/20 0.49
MAPT P10636 1/20 0.49
RXFP1 Q9HBX9 1/20 0.49
MEN1 O00255 2/20 0.49
LMNA P02545 1/20 0.49
THRB P10828 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7205122 0.93 KDM4A (0.76) KDM4AKDM4CHTR7SIGMAR1APP
SCHEMBL7398852 0.91 KDM4A (0.74) KDM4AKDM4CHTR7SIGMAR1APP
SCHEMBL25688953 0.88 CARM1 (0.72) KDM4AKDM4CHTR7CARM1PRMT6
SCHEMBL8342032 0.88 CARM1 (0.72) KDM4AKDM4CHTR7CARM1PRMT6
SCHEMBL8904225 0.88 KDM4A (0.56) KDM4AKDM4CHTR7CARM1PRMT6
SCHEMBL2676817 0.86 KDM4A (0.67) KDM4AKDM4CHTR7CARM1PRMT6
SCHEMBL4604745 0.86 CARM1 (0.75) CARM1PRMT6PRMT8SIGMAR1ACHE
Hydrochloric Acid SCHEMBL8891865 0.85 KDM4A (0.68) KDM4AKDM4CHTR7CARM1PRMT6
Hydrochloric Acid SCHEMBL9373710 0.85 CARM1 (0.72) KDM4AKDM4CHTR7CARM1PRMT6
Hydrochloric Acid SCHEMBL8905247 0.81 KDM4A (0.64) KDM4AKDM4CHTR7SIGMAR1APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5654421-A WASHING KITCHENWARE THE PROCTER & GAMBLE COMPANY (US) 1997-08-05 US disclosed
US-5578136-A AND A SOURCE OF HYDROGEN PEROXIDE; REMOVE TEA STAINS THE PROCTER & GAMBLE COMPANY (US) 1996-11-26 US disclosed