Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.75 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.75 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.75 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.68 |
| ▸ | MAOB | P27338 | 4/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25688953 | 0.98 | CARM1 (0.72) | CARM1PRMT6PRMT8SIGMAR1MAOB | |
| Hydrochloric Acid SCHEMBL9373710 | 0.98 | CARM1 (0.72) | CARM1PRMT6PRMT8SIGMAR1MAOB | |
| SCHEMBL8342032 | 0.98 | CARM1 (0.72) | CARM1PRMT6PRMT8SIGMAR1MAOB | |
| SCHEMBL2108172 | 0.94 | CARM1 (0.78) | CARM1PRMT6PRMT8SIGMAR1MAOB | |
| Hydrochloric Acid SCHEMBL18730544 | 0.92 | CARM1 (0.75) | CARM1PRMT6PRMT8SIGMAR1MAOB | |
| SCHEMBL7225346 | 0.88 | SIGMAR1 (0.85) | CARM1PRMT6PRMT8SIGMAR1MAOB | |
| SCHEMBL29733117 | 0.88 | SIGMAR1 (0.85) | CARM1PRMT6PRMT8SIGMAR1MAOB | |
| Aminocaproic Acid SCHEMBL8904221 | 0.86 | KDM4A (0.67) | CARM1PRMT6PRMT8SIGMAR1MAOB | |
| SCHEMBL1395704 | 0.86 | CARM1 (1.00) | CARM1PRMT6PRMT8SIGMAR1MAOB | |
| SCHEMBL1088446 | 0.86 | SIGMAR1 (0.74) | CARM1PRMT6PRMT8SIGMAR1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10639300-B2 | Compositions and methods for treating nasal and paranasal mucosa diseases with nicotinic acetylcholine receptor agonists | SOLIS HERRERA ARTURO (MX) | 2020-05-05 | — | — | US | disclosed |
| US-20190111038-A1 | COMPOSITIONS AND METHODS FOR TREATING NASAL AND PARANASAL MUCOSA DISEASES WITH NICOTINIC ACETYLCHOLINE RECEPTOR AGONISTS | SOLIS HERRERA ARTURO (MX) | 2019-04-18 | — | — | US | disclosed |
| EP-3442583-A2 | COMPOSITIONS AND METHODS FOR TREATING PARANASAL MUCOSA DISEASES WITH NICOTINIC ACETYLCHOLINE RECEPTOR AGONISTS | Solis Herrera, Arturo (MX) | 2019-02-20 | — | — | EP | disclosed |
| CN-109069649-A | Compositions and methods for treating nasal and paranasal mucosal disorders with nicotinic acetylcholine receptor agonists | A·索利斯·赫雷拉 | 2018-12-21 | — | — | CN | disclosed |
| WO-2017178897-A2 | COMPOSITIONS AND METHODS FOR TREATING PARANASAL MUCOSA DISEASES WITH NICOTINIC ACETYLCHOLINE RECEPTOR AGONISTS | SOLIS HERRERA ARTURO (MX) | 2017-10-19 | — | — | WO | disclosed |
| US-20170152213-A1 | AMINE-CONTAINING LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-06-01 | — | — | US | disclosed |
| US-20080306067-A1 | Modulators of Chemokine Receptor Activity | WEIGAND KLAUS | 2008-12-11 | — | — | US | disclosed |
| EP-1943235-A1 | ARYLUREA DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Novartis AG (CH) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007048771-A1 | ARYLUREA DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | NOVARTIS AG (CH) | 2007-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306067-A1 | Modulators of Chemokine Receptor Activity | CCR3, CCR1, CCR4 | CARM1 2415/4885PRMT6 2608/4885PRMT8 2472/4885 |
| US-20170152213-A1 | AMINE-CONTAINING LIPIDOIDS AND USES THEREOF | ABCB4, PHOSPHO1, SGMS2 | CARM1 699/4885PRMT6 665/4885PRMT8 1416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.