Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.42 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8369512 | 0.88 | S1PR3 (0.41) | SYKS1PR3ALDH1A1LMNAHTT | |
| SCHEMBL25834163 | 0.88 | S1PR3 (0.42) | SYKS1PR3ALDH1A1LMNAHTT | |
| SCHEMBL637735 | 0.86 | ATM (0.59) | ATMPRKCZFNTAFNTBSYK | |
| SCHEMBL1998566 | 0.86 | ATM (0.59) | ATMPRKCZFNTAFNTBSYK | |
| SCHEMBL21609291 | 0.84 | PTGFR (0.47) | ATMFNTAFNTBSYKALDH1A1 | |
| SCHEMBL29847988 | 0.84 | PTGFR (0.47) | ATMFNTAFNTBSYKALDH1A1 | |
| SCHEMBL21610487 | 0.84 | PTGFR (0.47) | ATMFNTAFNTBSYKALDH1A1 | |
| SCHEMBL21610500 | 0.84 | PTGFR (0.47) | ATMFNTAFNTBSYKALDH1A1 | |
| SCHEMBL7634732 | 0.84 | TSHR (0.53) | CYP26A1PRKCZFFAR1FNTAFNTB | |
| SCHEMBL8904412 | 0.84 | GPR139 (0.50) | ATMALDH1A1LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686609-A | Aromatic amine compounds, Their method of preparation and pharmaceutical compositions in which they are present | SANOFI (FR) | 1997-11-11 | — | — | US | disclosed |
| US-5618938-A | Process for preparing stereo isomers of neurokinin receptor antagonists | SANOFI (FR) | 1997-04-08 | — | — | US | disclosed |
| US-5317020-A | Neurokinin receiver antagonist as antiinflammatory agents | SANOFI (FR) | 1994-05-31 | — | — | US | disclosed |