Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 5/20 | 0.50 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.48 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8904504 | 1.00 | TK1 (0.50) | TK1RNASE1DHFR | |
| SCHEMBL8904703 | 0.86 | TK1 (0.62) | TK1 | |
| SCHEMBL8904705 | 0.86 | TK1 (0.62) | TK1 | |
| SCHEMBL8904709 | 0.86 | TK1 (0.62) | TK1 | |
| SCHEMBL10580671 | 0.86 | TK1 (0.53) | TK1RNASE1DHFR | |
| SCHEMBL8904506 | 0.85 | TK1 (0.47) | TK1RNASE1DHFR | |
| SCHEMBL8904501 | 0.85 | TK1 (0.47) | TK1RNASE1DHFR | |
| SCHEMBL9780934 | 0.82 | TK1 (0.41) | TK1RNASE1 | |
| SCHEMBL9780938 | 0.82 | TK1 (0.41) | TK1RNASE1 | |
| SCHEMBL9780941 | 0.82 | TK1 (0.41) | TK1RNASE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677439-A | PREVENTION GENE EXPRESSION | SANOFI (FR) | 1997-10-14 | — | — | US | disclosed |
| EP-0541722-B1 | COMPOUNDS AND METHODS FOR INHIBITING GENE EXPRESSION | STERLING WINTHROP INC (US) | 1995-12-20 | — | — | EP | disclosed |
| WO-1992002534-A2 | COMPOUNDS AND METHODS FOR INHIBITING GENE EXPRESSION | STERLING DRUG, INC. (US) | 1992-02-20 | — | — | WO | disclosed |