Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.44 |
| ▸ | ST14 | Q9Y5Y6 | 12/20 | 0.39 |
| ▸ | F2 | P00734 | 11/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 9/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 9/20 | 0.39 |
| ▸ | PLG | P00747 | 3/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.36 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8904049 | 0.89 | ITGB3 (0.45) | ITGB3ITGA2BST14F2PRSS1 | |
| SCHEMBL8904093 | 0.89 | ITGB3 (0.37) | ITGB3ITGA2BST14F2PRSS1 | |
| SCHEMBL8713033 | 0.85 | ITGB3 (0.43) | ITGB3ITGA2BST14F2PRSS1 | |
| SCHEMBL8904560 | 0.85 | ITGB3 (0.43) | ITGB3ITGA2BST14F2PRSS1 | |
| SCHEMBL8904039 | 0.83 | NPC1 (0.49) | ITGB3ITGA2BF2TPSAB1TPSD1 | |
| SCHEMBL8715729 | 0.83 | NPC1 (0.49) | ITGB3ITGA2BF2TPSAB1TPSD1 | |
| SCHEMBL8904683 | 0.80 | ITGB3 (0.43) | ITGB3ITGA2BST14F2PRSS1 | |
| SCHEMBL8906283 | 0.78 | ITGB3 (0.40) | ITGB3ITGA2BST14F2PRSS1 | |
| SCHEMBL8904670 | 0.76 | F2 (0.55) | ITGB3ITGA2BF2TPSAB1TPSD1 | |
| SCHEMBL8716704 | 0.76 | F2 (0.55) | ITGB3ITGA2BF2TPSAB1TPSD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5635527-A | ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES | THE GREEN CROSS CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0712844-A1 | NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-22 | — | — | EP | disclosed |