Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14952781 | 0.83 | TDP1 (0.63) | TDP1ALDH1A1KEAP1KMT2AFFAR1 | |
| SCHEMBL347597 | 0.81 | TDP1 (0.61) | TDP1ALDH1A1KEAP1KMT2AFFAR1 | |
| SCHEMBL27428759 | 0.81 | TDP1 (0.61) | TDP1ALDH1A1KEAP1KMT2AFFAR1 | |
| SCHEMBL705231 | 0.81 | TSHR (0.56) | ALDH1A1KMT2AHDAC8HDAC6KDM4E | |
| Acetic Acid SCHEMBL27752250 | 0.81 | TDP1 (0.56) | TDP1ALDH1A1KEAP1KMT2AFFAR1 | |
| SCHEMBL4642125 | 0.79 | TDP1 (0.58) | TDP1ALDH1A1KEAP1KMT2AFFAR1 | |
| Methyl 3-Phenylpropanoate SCHEMBL168711 | 0.79 | TDP1 (0.68) | TDP1ALDH1A1KEAP1KMT2AFFAR1 | |
| SCHEMBL29086538 | 0.78 | TDP1 (0.73) | TDP1ALDH1A1KEAP1KMT2AFFAR1 | |
| SCHEMBL1739439 | 0.78 | TDP1 (0.73) | TDP1ALDH1A1KEAP1KMT2AFFAR1 | |
| Ethyl 3-Phenylpropanoate SCHEMBL6847259 | 0.77 | TDP1 (0.66) | TDP1ALDH1A1TRPV1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020032080-A1 | COMPOUND, SALT OF COMPOUND, NEUROMODULATION AGENT, METHOD FOR EVALUATING NEUROMODULATION AGENT, METHOD FOR PRODUCING COMPOUND, AND METHOD FOR PRODUCING SALT OF COMPOUND | 学校法人慶應義塾 | 2020-02-13 | — | — | WO | disclosed |
| US-5633243-A | Anti-tumor platinum complexes, their preparation and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1997-05-27 | — | — | US | disclosed |
| US-5527905-A | RELATIVELY FEW SIDE EFFECTS, GOOD SOLUBILITY IN WATER | SANKYO COMPANY, LIMITED (JP) | 1996-06-18 | — | — | US | disclosed |
| EP-0290280-B1 | Anti-tumor platinum complexes, their preparation and their therapeutic use | SANKYO CO (JP) | 1994-01-19 | — | — | EP | disclosed |
| CN-1017803-B | ANTI-TUMOR PLATINUM COMPLEX AND PREPARATION THEREOF | SANKYO CO (JP) | 1992-08-12 | — | — | CN | disclosed |
| CN-1034544-A | Antineoplastic platinum complex, its preparation and therepic use | SANKYO CO (JP) | 1989-08-09 | — | — | CN | disclosed |
| EP-0290280-A2 | Anti-tumor platinum complexes, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1988-11-09 | — | — | EP | disclosed |