Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 1.00 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10856200 | 0.88 | KDM4E (0.79) | KDM4EHTTALDH1A1HSD17B10PKM | |
| SCHEMBL10775667 | 0.81 | KDM4E (0.68) | KDM4ELMNAALDH1A1GAAMGAM | |
| SCHEMBL10481129 | 0.81 | KDM4E (0.68) | KDM4EHTTFFAR1LMNACYP1A2 | |
| SCHEMBL10481117 | 0.79 | KDM4E (0.64) | KDM4EHTTFFAR1LMNARAB9A | |
| SCHEMBL10775927 | 0.79 | KDM4E (0.64) | KDM4EHTTFFAR1RAB9ASMN1; SMN2 | |
| SCHEMBL16431606 | 0.78 | KDM4E (0.63) | KDM4EHTTLMNAGAAMGAM | |
| SCHEMBL10481139 | 0.76 | KDM4E (0.61) | KDM4EHTTLMNASMN1; SMN2HIF1A | |
| SCHEMBL10481128 | 0.76 | KDM4E (0.60) | KDM4EHTTLMNARAB9ASMN1; SMN2 | |
| SCHEMBL10481173 | 0.76 | KDM4E (0.60) | KDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL10481100 | 0.76 | KDM4E (0.60) | KDM4EGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0099692-B1 | NEW FURANONE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-03-18 | — | — | EP | claimed |
| US-4585789-A | ALDOSE REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-04-29 | — | — | US | claimed |
| CN-120080630-A | Thermoplastic polyolefin interior trim skin with high chemical resistance and preparation method thereof | 苏州瑞高新材料股份有限公司 | 2025-06-03 | — | — | CN | disclosed |
| EP-4408967-A1 | BRANDY REPLICAS | AVA FOOD LABS, INC. (US) | 2024-08-07 | — | — | EP | disclosed |
| CN-118339274-A | Brandy replica | 艾娃食品实验室股份有限公司 | 2024-07-12 | — | — | CN | disclosed |
| WO-2023055801-A1 | BRANDY REPLICAS | AVA FOOD LABS, INC. (US) | 2023-04-06 | — | — | WO | disclosed |
| US-5698585-A | FOR SENILE CATARACT CAUSED BY OXIDATION DISORDER; VISION DEFECTS | KIKKOMAN CORPORATION (JP) | 1997-12-16 | — | — | US | disclosed |
| EP-0737476-A2 | A pharmaceutical preparation containing a 3-(2H)-furanone derivative for prevention and/or treatment of cataracts | KIKKOMAN CORPORATION (JP) | 1996-10-16 | — | — | EP | disclosed |
| EP-0526516-A1 | APPARATUS FOR AND METHOD OF STRUCTURING OR STORING DATA WITHIN A FILE | INTERNATIONAL UNION OF CRYSTALLOGRAPHY (GB) | 1993-02-10 | — | — | EP | disclosed |
| WO-1991016682-A1 | A METHOD OF STRUCTURING OR STORING DATA WITHIN A FILE | INTERNATIONAL UNION OF CRYSTALLOGRAPHY (GB) | 1991-10-31 | — | — | WO | disclosed |
| US-4797417-A | ALDOSE REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-01-10 | — | — | US | disclosed |
| EP-0099692-B1 | NEW FURANONE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-03-18 | — | — | EP | disclosed |
| EP-0189272-A2 | New furanone derivatives, processes for preparation thereof and use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-07-30 | — | — | EP | disclosed |
| US-4585789-A | ALDOSE REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-04-29 | — | — | US | disclosed |
| EP-0099692-A1 | New furanone derivatives, process for the preparation thereof and use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-02-01 | — | — | EP | disclosed |