Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10775773 | 0.92 | KDM4E (0.58) | KDM4ENAAADAOLMNATSHR | |
| SCHEMBL10481138 | 0.83 | KDM4E (0.40) | KDM4ENAAALMNATSHRPDE4D | |
| SCHEMBL16431606 | 0.78 | KDM4E (0.63) | KDM4ELMNATSHRMGAMGAA | |
| SCHEMBL10775667 | 0.76 | KDM4E (0.68) | KDM4ELMNATSHRALDH1A1MGAM | |
| SCHEMBL8181781 | 0.70 | LMNA (0.46) | NAAALMNATSHRPDE4DALDH1A1 | |
| SCHEMBL6719657 | 0.69 | TSHR (0.41) | NAAADAOLMNATSHRPDE4D | |
| SCHEMBL15239316 | 0.69 | TAAR1 (0.41) | NAAALMNATSHRPDE4DALDH1A1 | |
| SCHEMBL1459289 | 0.68 | LMNA (0.49) | NAAADAOLMNATSHRPDE4D | |
| SCHEMBL1459291 | 0.68 | LMNA (0.49) | NAAADAOLMNATSHRPDE4D | |
| SCHEMBL6933176 | 0.66 | KDM4E (0.45) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0189272-A2 | New furanone derivatives, processes for preparation thereof and use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-07-30 | — | — | EP | claimed |
| US-4797417-A | ALDOSE REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-01-10 | — | — | US | disclosed |
| EP-0189272-A2 | New furanone derivatives, processes for preparation thereof and use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-07-30 | — | — | EP | disclosed |