Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | YAP1 | P46937 | 5/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GPR34 | Q9UPC5 | 3/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8904696 | 1.00 | SMN1; SMN2 (0.51) | SMN1; SMN2CYP2C19YAP1FOLH1NPC1 | |
| SCHEMBL8717621 | 0.88 | YAP1 (0.47) | SMN1; SMN2CYP2C19YAP1FOLH1NPC1 | |
| SCHEMBL8717617 | 0.88 | YAP1 (0.47) | SMN1; SMN2CYP2C19YAP1FOLH1NPC1 | |
| SCHEMBL77520 | 0.76 | SMN1; SMN2 (0.67) | SMN1; SMN2CYP2C19NPC1RAB9AGRIN2B | |
| SCHEMBL8379176 | 0.76 | SMN1; SMN2 (0.57) | SMN1; SMN2CYP2C19NPC1RAB9ACETP | |
| SCHEMBL3898927 | 0.76 | YAP1 (0.61) | YAP1ITGB3ITGA2B | |
| SCHEMBL9417257 | 0.75 | POLB (0.67) | SMN1; SMN2CYP2C19YAP1FOLH1NPC1 | |
| SCHEMBL13198831 | 0.75 | SMN1; SMN2 (0.63) | SMN1; SMN2CYP2C19NPC1RAB9AGRIN2B | |
| SCHEMBL4111065 | 0.74 | HTT (0.65) | SMN1; SMN2CYP2C19NPC1RAB9AGRIN2B | |
| SCHEMBL13677224 | 0.74 | SMN1; SMN2 (0.64) | SMN1; SMN2CYP2C19NPC1RAB9AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5635527-A | ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES | THE GREEN CROSS CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0712844-A1 | NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-22 | — | — | EP | disclosed |