Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8395430 | 0.95 | AGTR1 (0.48) | AGTR1AGTR2PPARG | |
| Trifluoroacetic Acid SCHEMBL8394600 | 0.89 | AGTR1 (0.43) | AGTR1AGTR2PPARG | |
| Trifluoroacetic Acid SCHEMBL8395903 | 0.88 | AGTR1 (0.45) | AGTR1AGTR2 | |
| Trifluoroacetic Acid SCHEMBL8393012 | 0.86 | AGTR1 (0.40) | AGTR1AGTR2PPARG | |
| SCHEMBL8392247 | 0.86 | AGTR1 (0.49) | AGTR1AGTR2PPARG | |
| SCHEMBL8396973 | 0.85 | AGTR1 (0.46) | AGTR1AGTR2 | |
| Trifluoroacetic Acid SCHEMBL8392505 | 0.85 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL8396008 | 0.85 | AGTR1 (0.48) | AGTR1AGTR2PPARG | |
| SCHEMBL8391694 | 0.85 | AGTR1 (0.53) | AGTR1AGTR2PPARG | |
| SCHEMBL8391405 | 0.85 | AGTR1 (0.49) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684029-A | HYPOTENSIVE AGENTS | KARL THOMAE GMBH (DE) | 1997-11-04 | — | — | US | disclosed |