SCHEMBL8905243

SCHEMBL8905243

CCC(C)(N)C=CC(=O)N(C)[C@H](Cc1ccc2ccccc2c1)C(=O)N(C)[C@@H](CNC(=S)NC1CC1)Cc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GHSR Q92847 7/20 0.45
TACR1 P25103 2/20 0.39
OPRM1 P35372 3/20 0.36
BDKRB2 P30411 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6319133 0.89 GHSR (0.53) GHSRTACR1OPRM1
SCHEMBL6319124 0.89 GHSR (0.53) GHSRTACR1OPRM1
SCHEMBL7060365 0.85 GHSR (0.55) GHSRTACR1OPRM1
SCHEMBL7060362 0.85 GHSR (0.55) GHSRTACR1OPRM1
SCHEMBL6317128 0.85 TACR1 (0.45) GHSRTACR1OPRM1BDKRB2
SCHEMBL6317870 0.83 TACR1 (0.41) GHSRTACR1OPRM1BDKRB2
SCHEMBL6316483 0.82 GHSR (0.52) GHSRTACR1
SCHEMBL6316485 0.82 GHSR (0.52) GHSRTACR1
SCHEMBL6317497 0.79 TACR1 (0.41) TACR1OPRM1BDKRB2
SCHEMBL8905882 0.78 GHSR (0.49) GHSRTACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997023508-A1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK A/S (DK) 1997-07-03 WO claimed