Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8906951 | 0.83 | AGTR1 (0.39) | AGTR1AGTR2PPARG | |
| Trifluoroacetic Acid SCHEMBL9097601 | 0.80 | AGTR1 (0.61) | AGTR1AGTR2PPARG | |
| SCHEMBL8907060 | 0.79 | AGTR1 (0.39) | AGTR1AGTR2 | |
| SCHEMBL8905662 | 0.79 | AGTR1 (0.39) | AGTR1AGTR2 | |
| SCHEMBL8906972 | 0.79 | AGTR1 (0.39) | AGTR1AGTR2 | |
| Trifluoroacetic Acid SCHEMBL8788413 | 0.77 | AGTR1 (0.47) | AGTR1AGTR2PPARG | |
| SCHEMBL8906906 | 0.76 | AGTR1 (0.39) | AGTR1AGTR2PPARG | |
| Trifluoroacetic Acid SCHEMBL8905360 | 0.76 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL8905229 | 0.76 | AGTR1 (0.36) | AGTR1AGTR2 | |
| SCHEMBL8905890 | 0.75 | AGTR1 (0.38) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684029-A | HYPOTENSIVE AGENTS | KARL THOMAE GMBH (DE) | 1997-11-04 | — | — | US | disclosed |