SCHEMBL8905486

CN(C(=O)[C@@H](Cc1ccc2ccccc2c1)N(C)C(=O)/C=C/CC(C)(C)NC(=O)O)[C@@H](CNS(C)(=O)=O)Cc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	GHSR	Q92847	8/20	0.60

▸	OPRM1	P35372	4/20	0.34

▸	OPRD1	P41143	1/20	0.33

▸	OPRK1	P41145	1/20	0.33

▸	F2	P00734	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8905496	1.00	GHSR (0.60)	GHSROPRM1OPRD1OPRK1F2
SCHEMBL6325851	0.92	GHSR (0.56)	GHSROPRM1
SCHEMBL6318040	0.92	GHSR (0.56)	GHSROPRM1
SCHEMBL6318920	0.91	GHSR (0.63)	GHSROPRM1F2
SCHEMBL6318044	0.91	GHSR (0.63)	GHSROPRM1F2
SCHEMBL7060362	0.83	GHSR (0.55)	GHSROPRM1
SCHEMBL7060365	0.83	GHSR (0.55)	GHSROPRM1
SCHEMBL7066041	0.82	GHSR (0.46)	GHSROPRM1F2
SCHEMBL7131016	0.81	GHSR (0.54)	GHSROPRM1
SCHEMBL7131022	0.81	GHSR (0.54)	GHSROPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-1997023508-A1	COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES	NOVO NORDISK A/S (DK)	1997-07-03	—	—	WO	disclosed