Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 16/20 | 0.61 |
| ▸ | HTR2C | P28335 | 13/20 | 0.57 |
| ▸ | HTR7 | P34969 | 2/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905551 | 0.88 | HTR2B (0.56) | HTR2AHTR2CHTR7CHRM4HTR2B | |
| SCHEMBL8907199 | 0.87 | HTR7 (0.63) | HTR2AHTR2CHTR7CHRM4 | |
| SCHEMBL8907039 | 0.83 | HTR2A (0.62) | HTR2AHTR2CHTR7CHRM4 | |
| SCHEMBL8905515 | 0.83 | HTR2A (0.59) | HTR2AHTR2CHTR7CHRM4HTR2B | |
| SCHEMBL764805 | 0.79 | HTR2A (0.71) | HTR2AHTR2CHTR2B | |
| SCHEMBL8402972 | 0.77 | HTR2A (1.00) | HTR2AHTR2CHTR7CHRM4 | |
| SCHEMBL23405100 | 0.75 | HTR2A (0.78) | HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL23405129 | 0.74 | HTR2A (0.79) | HTR2AHTR2CHTR2B | |
| SCHEMBL21731571 | 0.74 | HTR2A (0.76) | HTR2AHTR2CHTR2B | |
| SCHEMBL21731842 | 0.74 | HTR2A (0.76) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997000871-A1 | TETRAHYDRO-BETACARBOLINE DERIVATIVES AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1997-01-09 | — | — | WO | claimed |
| WO-1997000871-A1 | TETRAHYDRO-BETACARBOLINE DERIVATIVES AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1997-01-09 | — | — | WO | disclosed |