Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 15/20 | 0.43 |
| ▸ | F2 | P00734 | 5/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 5/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8904170 | 0.90 | ITGB3 (0.40) | ITGB3ITGA2BF2ST14PRSS1 | |
| SCHEMBL8904719 | 0.88 | F2 (0.41) | ITGB3ITGA2BF2ST14PRSS1 | |
| SCHEMBL8904035 | 0.85 | F2 (0.39) | ITGB3ITGA2BF2ST14PRSS1 | |
| SCHEMBL8904683 | 0.85 | ITGB3 (0.43) | ITGB3ITGA2BF2ST14PRSS1 | |
| SCHEMBL8904747 | 0.84 | ST14 (0.39) | F2ST14PRSS1PRSS2PRSS3 | |
| SCHEMBL8904003 | 0.82 | ITGB3 (0.48) | ITGB3ITGA2BF2ST14PRSS1 | |
| SCHEMBL8904820 | 0.81 | ST14 (0.38) | F2ST14PRSS1PRSS2PRSS3 | |
| SCHEMBL8904382 | 0.81 | ST14 (0.41) | ITGB3ITGA2BF2ST14PRSS1 | |
| SCHEMBL8905580 | 0.81 | ITGB3 (0.57) | ITGB3ITGA2BF2 | |
| SCHEMBL8905570 | 0.81 | ITGB3 (0.57) | ITGB3ITGA2BF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5635527-A | ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES | THE GREEN CROSS CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0712844-A1 | NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-22 | — | — | EP | disclosed |