Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905966 | 0.95 | AGTR1 (0.47) | PPARGAGTR1AGTR2 | |
| SCHEMBL8905754 | 0.89 | PPARG (0.44) | PPARGKDM4EABCC3ABCC4USP2 | |
| SCHEMBL8906844 | 0.88 | PPARG (0.45) | PPARGKDM4EABCC3ABCC4USP2 | |
| SCHEMBL8905710 | 0.87 | PPARG (0.57) | PPARGKDM4EABCC3ABCC4USP2 | |
| SCHEMBL8906835 | 0.87 | AGTR1 (0.49) | PPARGAGTR1AGTR2 | |
| SCHEMBL8906482 | 0.87 | PPARG (0.43) | PPARGKDM4EABCC3ABCC4USP2 | |
| SCHEMBL8906321 | 0.86 | PPARG (0.51) | PPARGKDM4EABCC3ABCC4USP2 | |
| SCHEMBL8905980 | 0.85 | PPARG (0.51) | PPARGKDM4EABCC3ABCC4USP2 | |
| SCHEMBL8905609 | 0.84 | PPARG (0.41) | PPARGKDM4EABCC3ABCC4USP2 | |
| SCHEMBL8905389 | 0.83 | PPARG (0.53) | PPARGKDM4EABCC3ABCC4USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684029-A | HYPOTENSIVE AGENTS | KARL THOMAE GMBH (DE) | 1997-11-04 | — | — | US | disclosed |