Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.41 |
| ▸ | TST | Q16762 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.40 |
| ▸ | ACP1 | P24666 | 2/20 | 0.40 |
| ▸ | CDC25B | P30305 | 2/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.40 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.40 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.40 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.40 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.40 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905325 | 1.00 | PRKCA (0.41) | PRKCAMAPTRECQLTDP1HSPD1 | |
| SCHEMBL8905344 | 1.00 | PRKCA (0.41) | PRKCAMAPTRECQLTDP1HSPD1 | |
| SCHEMBL8905727 | 1.00 | PRKCA (0.41) | PRKCAMAPTRECQLTDP1HSPD1 | |
| SCHEMBL8905186 | 1.00 | PRKCA (0.41) | PRKCAMAPTRECQLTDP1HSPD1 | |
| SCHEMBL8905907 | 1.00 | PRKCA (0.41) | PRKCAMAPTRECQLTDP1HSPD1 | |
| SCHEMBL8904013 | 1.00 | PRKCA (0.41) | PRKCAMAPTRECQLTDP1HSPD1 | |
| SCHEMBL8906517 | 1.00 | PRKCA (0.41) | PRKCAMAPTRECQLTDP1HSPD1 | |
| SCHEMBL8904855 | 1.00 | PRKCA (0.41) | PRKCAMAPTRECQLTDP1HSPD1 | |
| SCHEMBL8905003 | 1.00 | PRKCA (0.41) | PRKCAMAPTRECQLTDP1HSPD1 | |
| SCHEMBL8903985 | 1.00 | PRKCA (0.41) | PRKCAMAPTRECQLTDP1HSPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698585-A | FOR SENILE CATARACT CAUSED BY OXIDATION DISORDER; VISION DEFECTS | KIKKOMAN CORPORATION (JP) | 1997-12-16 | — | — | US | disclosed |
| EP-0737476-A2 | A pharmaceutical preparation containing a 3-(2H)-furanone derivative for prevention and/or treatment of cataracts | KIKKOMAN CORPORATION (JP) | 1996-10-16 | — | — | EP | disclosed |