Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.61 |
| ▸ | PIM1 | P11309 | 3/20 | 0.61 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.61 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.61 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.61 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.59 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.53 |
| ▸ | IGF1R | P08069 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | SI | P14410 | 1/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8307819 | 0.85 | DYRK1A (0.61) | DYRK1APIM1PIM3PIM2DYRK2 | |
| SCHEMBL8307815 | 0.85 | DYRK1A (0.61) | DYRK1APIM1PIM3PIM2DYRK2 | |
| SCHEMBL8307820 | 0.79 | DYRK1A (0.61) | DYRK1APIM1PIM3PIM2DYRK2 | |
| SCHEMBL9472266 | 0.77 | EGFR (0.67) | DYRK1APIM1PIM3PIM2DYRK2 | |
| SCHEMBL9472275 | 0.77 | EGFR (0.67) | DYRK1APIM1PIM3PIM2DYRK2 | |
| SCHEMBL29377541 | 0.76 | PIM1 (1.00) | DYRK1APIM1PIM3PIM2DYRK2 | |
| SCHEMBL8165608 | 0.76 | PIM1 (1.00) | DYRK1APIM1PIM3PIM2DYRK2 | |
| SCHEMBL8165609 | 0.76 | PIM1 (1.00) | DYRK1APIM1PIM3PIM2DYRK2 | |
| SCHEMBL15421616 | 0.76 | PIM1 (1.00) | DYRK1APIM1PIM3PIM2DYRK2 | |
| SCHEMBL8311581 | 0.75 | PDE4B (1.00) | DYRK1APIM1PIM3PIM2DYRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5661168-A | ADMINISTERING RHODANINE DERIVATIVES TO CONTROL DIABETES | ELI LILLY AND COMPANY (US) | 1997-08-26 | — | — | US | disclosed |