Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 18/20 | 0.43 |
| ▸ | RXRB | P28702 | 9/20 | 0.41 |
| ▸ | RXRG | P48443 | 9/20 | 0.41 |
| ▸ | RARA | P10276 | 3/20 | 0.41 |
| ▸ | RARB | P10826 | 3/20 | 0.41 |
| ▸ | RARG | P13631 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5947942 | 0.84 | RXRA (0.44) | RXRARXRBRXRGRARARARB | |
| SCHEMBL8906014 | 0.82 | RXRA (0.44) | RXRARXRBRXRGRARARARB | |
| SCHEMBL8906033 | 0.81 | RXRA (0.40) | RXRARXRBRXRGRARARARB | |
| SCHEMBL8905375 | 0.81 | RXRA (0.40) | RXRARXRBRXRGRARARARB | |
| SCHEMBL7195766 | 0.76 | RARG (0.48) | RXRARXRBRXRGRARARARB | |
| SCHEMBL22001266 | 0.73 | RXRA (0.54) | RXRARXRBRXRGRARARARB | |
| SCHEMBL20610569 | 0.73 | RXRA (0.44) | RXRARXRBRXRGRARARARB | |
| SCHEMBL9054943 | 0.72 | RXRA (0.48) | RXRARXRBRXRGRARARARB | |
| SCHEMBL8014224 | 0.72 | RXRA (0.50) | RXRARXRBRXRGRARARARB | |
| SCHEMBL9054911 | 0.72 | RXRA (0.46) | RXRARXRBRXRGRARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700836-A | TOPICALLY ADMINISTERING TO TREAT PHOTODAMAGED SKIN | HOFFMANN-LA ROCHE INC. (US) | 1997-12-23 | — | — | US | disclosed |