Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.62 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.40 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR5A | P47898 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8347348 | 0.98 | OPRM1 (0.65) | OPRM1OPRL1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL10529109 | 0.88 | OPRM1 (0.71) | OPRM1OPRL1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL15863283 | 0.85 | OPRM1 (0.68) | OPRM1OPRL1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL7382986 | 0.85 | OPRM1 (0.68) | OPRM1OPRL1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL3519309 | 0.83 | OPRM1 (0.66) | OPRM1OPRL1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL3521102 | 0.79 | OPRM1 (0.61) | OPRM1OPRL1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL187469 | 0.79 | OPRM1 (0.55) | OPRM1OPRL1 | |
| SCHEMBL3518561 | 0.78 | OPRM1 (0.63) | OPRM1OPRL1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL3518560 | 0.78 | OPRM1 (0.63) | OPRM1OPRL1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL13253932 | 0.78 | OPRM1 (0.59) | OPRM1OPRL1SLC6A4SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5661160-A | ADMINISTERING AN ANTITUSSIVE AGENT FOR TREATING COUGH; TACHYKININ ANTAGONISM, SUBSTANCE P AND NEUROKININ A ANTAGONISM | MERRELL PHARMACEUTICALS INC. (US) | 1997-08-26 | — | — | US | disclosed |