Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45095 | 0.86 | KMT2A (0.30) | — | |
| SCHEMBL4649342 | 0.84 | NPC1 (0.36) | GABRA1GABRG2GABRB3NOTUM | |
| SCHEMBL9292940 | 0.81 | GSTP1 (0.36) | GSTP1GABRA1GABRG2GABRB3SLC6A3 | |
| SCHEMBL36556 | 0.77 | GSTP1 (0.45) | GSTP1TSHRNOTUMPGRHDAC4 | |
| SCHEMBL1758350 | 0.77 | GSTP1 (0.45) | GSTP1TSHRNOTUMPGRHDAC4 | |
| Ethylene Glycol SCHEMBL6034298 | 0.77 | POLB (0.30) | — | |
| SCHEMBL533284 | 0.77 | GSTP1 (0.39) | GSTP1GABRA1GABRG2GABRB3NOTUM | |
| SCHEMBL28085447 | 0.74 | LMNA (0.32) | — | |
| SCHEMBL850248 | 0.74 | — | — | |
| SCHEMBL28796146 | 0.74 | NPC1 (0.30) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4876378-A | Recovery of dialkyl naphthalene-2,6-dicarboxylates from naphthalene-2,6-dicarboxylic acid-containing polyesters | EASTMAN KODAK COMPANY (US) | 1989-10-24 | — | — | US | claimed |
| US-5607757-A | Paper machine fabric | EASTMAN CHEMICAL COMPANY (US) | 1997-03-04 | — | — | US | disclosed |