Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8906640 | 0.86 | AGTR1 (0.45) | AGTR1AGTR2PPARG | |
| SCHEMBL8906180 | 0.84 | AGTR1 (0.39) | AGTR1AGTR2PPARG | |
| SCHEMBL8905418 | 0.83 | AGTR1 (0.48) | AGTR1AGTR2PPARG | |
| SCHEMBL8906790 | 0.82 | AGTR1 (0.42) | AGTR1AGTR2PPARG | |
| SCHEMBL8393417 | 0.81 | AGTR1 (0.42) | AGTR1AGTR2PPARG | |
| SCHEMBL8906803 | 0.79 | AGTR1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL8905815 | 0.79 | PPARG (0.43) | AGTR1AGTR2PPARG | |
| SCHEMBL8906716 | 0.79 | AGTR1 (0.53) | AGTR1AGTR2PPARG | |
| SCHEMBL9096878 | 0.79 | AGTR1 (0.69) | AGTR1AGTR2PPARG | |
| SCHEMBL8905664 | 0.79 | AGTR1 (0.44) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684029-A | HYPOTENSIVE AGENTS | KARL THOMAE GMBH (DE) | 1997-11-04 | — | — | US | disclosed |