Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907244 | 0.94 | F2 (0.36) | F2CNR2NPSR1L3MBTL1CYP1A2 | |
| SCHEMBL8905159 | 0.83 | F2 (0.38) | F2CNR2NPSR1L3MBTL1CYP1A2 | |
| SCHEMBL8789752 | 0.80 | PPARG (0.41) | — | |
| SCHEMBL8905594 | 0.78 | PPARG (0.39) | F2CNR2NPSR1L3MBTL1CYP1A2 | |
| SCHEMBL8905630 | 0.78 | KDM4E (0.39) | NPSR1L3MBTL1CYP3A4CYP2C9HTT | |
| SCHEMBL8905456 | 0.77 | AGTR1 (0.42) | — | |
| SCHEMBL8907048 | 0.75 | AGTR1 (0.42) | ALDH1A1 | |
| SCHEMBL8905932 | 0.75 | BRD9 (0.34) | CYP3A4CYP2C9CYP2C19TSHRSMN1; SMN2 | |
| SCHEMBL8789968 | 0.75 | PPARG (0.49) | — | |
| SCHEMBL8905859 | 0.73 | AGTR1 (0.44) | ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684029-A | HYPOTENSIVE AGENTS | KARL THOMAE GMBH (DE) | 1997-11-04 | — | — | US | disclosed |