Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.46 |
| ▸ | TYMP | P19971 | 2/20 | 0.45 |
| ▸ | NT5E | P21589 | 2/20 | 0.43 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.42 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | DUT | P33316 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10491019 | 0.97 | POLB (0.54) | POLBABL1RIN1TYMPNT5E | |
| SCHEMBL5925303 | 0.95 | POLB (0.56) | POLBABL1RIN1TYMPNT5E | |
| SCHEMBL5358852 | 0.95 | POLB (0.56) | POLBABL1RIN1TYMPNT5E | |
| SCHEMBL1527090 | 0.94 | POLB (0.57) | POLBABL1RIN1TYMPNT5E | |
| SCHEMBL11134759 | 0.91 | POLB (0.53) | POLBABL1RIN1TYMPNT5E | |
| SCHEMBL2368809 | 0.91 | POLB (0.53) | POLBABL1RIN1TYMPNT5E | |
| SCHEMBL24115327 | 0.91 | TYMP (0.48) | POLBABL1RIN1TYMPNT5E | |
| SCHEMBL31556049 | 0.91 | TYMP (0.48) | POLBABL1RIN1TYMPNT5E | |
| SCHEMBL20596260 | 0.91 | TYMP (0.48) | POLBABL1RIN1TYMPNT5E | |
| SCHEMBL31556085 | 0.91 | TYMP (0.48) | POLBABL1RIN1TYMPNT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5695979-A | USING OLIGONUCLEOTIDE | COMPETITIVE TECHNOLOGIES, INC. (US) | 1997-12-09 | — | — | US | disclosed |
| US-5453496-A | Viricides | UNIVERSITY PATENTS, INC. (US) | 1995-09-26 | — | — | US | disclosed |
| US-5278302-A | Monophosphates | UNIVERSITY PATENTS, INC. (US) | 1994-01-11 | — | — | US | disclosed |
| EP-0378615-A4 | NUCLEOSIDE AND POLYNUCLEOTIDE THIOPHOSPHORAMIDITE AND PHOSPHORODITHIOATE COMPOUNDS AND PROCESSES | — | 1992-04-08 | — | — | EP | disclosed |
| EP-0463712-A2 | Polynucleotide phosphorodithioates as therapeutic agents for retroviral infections | UNIVERSITY PATENTS, INC. (US) | 1992-01-02 | — | — | EP | disclosed |
| WO-1990012022-A1 | POLYNUCLEOTIDE PHOSPHORODITHIOATES AS THERAPEUTIC AGENTS FOR RETROVIRAL INFECTIONS | UNIVERSITY PATENTS, INC. (US) | 1990-10-18 | — | — | WO | disclosed |
| EP-0378615-A1 | NUCLEOSIDE AND POLYNUCLEOTIDE THIOPHOSPHORAMIDITE AND PHOSPHORODITHIOATE COMPOUNDS AND PROCESSES | COMPETITIVE TECHNOLOGIES INC. (US) | 1990-07-25 | — | — | EP | disclosed |
| WO-1989011486-A1 | NUCLEOSIDE AND POLYNUCLEOTIDE THIOPHOSPHORAMIDITE AND PHOSPHORODITHIOATE COMPOUNDS AND PROCESSES | UNIVERSITY PATENTS, INC. (US) | 1989-11-30 | — | — | WO | disclosed |