Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.47 |
| ▸ | TYMP | P19971 | 3/20 | 0.45 |
| ▸ | NT5E | P21589 | 2/20 | 0.44 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.44 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | DUT | P33316 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11134759 | 1.00 | POLB (0.53) | POLBABL1RIN1TYMPNT5E | |
| SCHEMBL5358852 | 0.94 | POLB (0.56) | POLBABL1RIN1TYMPNT5E | |
| SCHEMBL5925303 | 0.94 | POLB (0.56) | POLBABL1RIN1TYMPNT5E | |
| SCHEMBL10491019 | 0.93 | POLB (0.54) | POLBABL1RIN1TYMPNT5E | |
| SCHEMBL8655916 | 0.92 | POLB (0.62) | POLBABL1RIN1TYMPNT5E | |
| SCHEMBL8655914 | 0.92 | POLB (0.62) | POLBABL1RIN1TYMPNT5E | |
| SCHEMBL8906384 | 0.91 | POLB (0.51) | POLBABL1RIN1TYMPNT5E | |
| SCHEMBL1527090 | 0.91 | POLB (0.57) | POLBABL1RIN1TYMPNT5E | |
| SCHEMBL24115327 | 0.88 | TYMP (0.48) | POLBABL1RIN1TYMPNT5E | |
| SCHEMBL20596260 | 0.88 | TYMP (0.48) | POLBABL1RIN1TYMPNT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106114-A1 | IDENTIFICATION OF HUMAN T2R RECEPTORS AND THE USE THEREOF TO IDENTIFY INHIBITORS (BLOCKERS) OF BITTER TASTE | SENOMYX, INC. (US) | 2011-09-01 | — | — | WO | disclosed |