Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 12/20 | 0.57 |
| ▸ | EDNRB | P24530 | 10/20 | 0.57 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8952066 | 0.95 | EDNRA (0.51) | EDNRAEDNRBAGTR1 | |
| SCHEMBL8952067 | 0.89 | EDNRA (0.54) | EDNRAEDNRB | |
| SCHEMBL8907237 | 0.88 | EDNRA (0.71) | EDNRAEDNRB | |
| SCHEMBL8906905 | 0.87 | EDNRA (0.52) | EDNRAEDNRBAGTR1 | |
| SCHEMBL8907782 | 0.87 | EDNRA (0.63) | EDNRAEDNRB | |
| Potassium SCHEMBL9263403 | 0.84 | EDNRB (0.57) | EDNRAEDNRB | |
| SCHEMBL9263398 | 0.84 | EDNRB (0.57) | EDNRAEDNRB | |
| SCHEMBL7333006 | 0.83 | EDNRA (0.79) | EDNRAEDNRBAGTR1 | |
| Potassium SCHEMBL8952100 | 0.82 | KMT2A (0.52) | EDNRAEDNRB | |
| SCHEMBL8952097 | 0.82 | KMT2A (0.52) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995003295-A1 | ENDOTHELIN ANTAGONISTS | MERCK & CO., INC. (US) | 1995-02-02 | — | — | WO | claimed |
| US-5686478-A | Endothelin antagonists | MERCK & CO. INC. (US) | 1997-11-11 | — | — | US | disclosed |
| WO-1995003295-A1 | ENDOTHELIN ANTAGONISTS | MERCK & CO., INC. (US) | 1995-02-02 | — | — | WO | disclosed |