Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907237 | 0.92 | EDNRA (0.71) | EDNRAEDNRB | |
| SCHEMBL8906644 | 0.87 | EDNRA (0.57) | EDNRAEDNRB | |
| SCHEMBL8906175 | 0.86 | EDNRA (0.59) | EDNRAEDNRB | |
| SCHEMBL8952158 | 0.85 | EDNRA (0.53) | EDNRAEDNRB | |
| SCHEMBL7329183 | 0.85 | EDNRA (0.86) | EDNRAEDNRB | |
| SCHEMBL8709959 | 0.83 | EDNRA (0.43) | EDNRAEDNRB | |
| SCHEMBL8906905 | 0.82 | EDNRA (0.52) | EDNRAEDNRB | |
| SCHEMBL8952066 | 0.81 | EDNRA (0.51) | EDNRAEDNRB | |
| SCHEMBL7338911 | 0.79 | EDNRA (0.77) | EDNRAEDNRB | |
| SCHEMBL7338403 | 0.79 | EDNRA (0.72) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995003295-A1 | ENDOTHELIN ANTAGONISTS | MERCK & CO., INC. (US) | 1995-02-02 | — | — | WO | claimed |
| US-5686478-A | Endothelin antagonists | MERCK & CO. INC. (US) | 1997-11-11 | — | — | US | disclosed |
| WO-1995003295-A1 | ENDOTHELIN ANTAGONISTS | MERCK & CO., INC. (US) | 1995-02-02 | — | — | WO | disclosed |