Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905658 | 0.90 | LMNA (0.42) | LMNACYP2C19HIF1AABCB1TDP1 | |
| SCHEMBL621765 | 0.89 | LMNA (0.42) | LMNACYP2C19HIF1AABCB1 | |
| SCHEMBL8905420 | 0.88 | LMNA (0.54) | LMNACYP2C19HIF1AABCB1 | |
| SCHEMBL8063052 | 0.85 | LMNA (0.36) | LMNACYP2C19HIF1AABCB1TDP1 | |
| Hydrochloric Acid SCHEMBL8857263 | 0.84 | LMNA (0.35) | LMNACYP2C19HIF1AABCB1TDP1 | |
| SCHEMBL9009279 | 0.83 | LMNA (0.49) | LMNACYP2C19HIF1AABCB1TDP1 | |
| SCHEMBL12845800 | 0.83 | LMNA (0.58) | LMNACYP2C19HIF1AABCB1TDP1 | |
| SCHEMBL8763555 | 0.82 | LMNA (0.42) | LMNACYP2C19HIF1AABCB1TDP1 | |
| SCHEMBL13797744 | 0.81 | LMNA (0.55) | LMNACYP2C19HIF1AABCB1 | |
| SCHEMBL24217642 | 0.80 | LMNA (0.41) | LMNACYP2C19HIF1AABCB1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698739-A | RADIOLOGY | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-12-16 | — | — | US | disclosed |