Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905700 | 0.94 | PPARG (0.50) | ALDH1A1KDM4EHSD17B10PPARGABCC3 | |
| SCHEMBL8906713 | 0.92 | AGTR1 (0.45) | ALDH1A1KDM4EHSD17B10PPARGABCC3 | |
| SCHEMBL8905690 | 0.88 | PPARG (0.47) | ALDH1A1KDM4EHSD17B10PPARGABCC3 | |
| SCHEMBL8905974 | 0.88 | PPARG (0.45) | ALDH1A1KDM4EHSD17B10PPARGABCC3 | |
| SCHEMBL8906316 | 0.87 | PPARG (0.44) | ALDH1A1KDM4EHSD17B10PPARGABCC3 | |
| SCHEMBL8906533 | 0.85 | PPARG (0.43) | ALDH1A1KDM4EHSD17B10PPARGABCC3 | |
| SCHEMBL8905384 | 0.85 | PPARG (0.46) | ALDH1A1KDM4EHSD17B10PPARGABCC3 | |
| SCHEMBL8906955 | 0.85 | PPARG (0.42) | ALDH1A1KDM4EHSD17B10PPARGABCC3 | |
| SCHEMBL8905585 | 0.84 | PPARG (0.43) | ALDH1A1KDM4EHSD17B10PPARGABCC3 | |
| SCHEMBL8905537 | 0.83 | DHODH (0.43) | ALDH1A1KDM4EHSD17B10PPARGABCC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684029-A | HYPOTENSIVE AGENTS | KARL THOMAE GMBH (DE) | 1997-11-04 | — | — | US | disclosed |