Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907094 | 0.95 | PPARG (0.40) | AGTR1AGTR2PPARGF10 | |
| SCHEMBL8906643 | 0.92 | AGTR1 (0.38) | AGTR1AGTR2PPARG | |
| SCHEMBL8906652 | 0.88 | PPARG (0.37) | AGTR1AGTR2PPARG | |
| SCHEMBL8906986 | 0.85 | AGTR1 (0.46) | AGTR1AGTR2PPARG | |
| SCHEMBL8907086 | 0.84 | PPARG (0.38) | AGTR1AGTR2PPARG | |
| SCHEMBL8906713 | 0.84 | AGTR1 (0.45) | AGTR1AGTR2PPARG | |
| SCHEMBL8906659 | 0.83 | PPARG (0.37) | AGTR1AGTR2PPARG | |
| SCHEMBL8905963 | 0.82 | AGTR1 (0.41) | AGTR1AGTR2PPARG | |
| SCHEMBL8905662 | 0.82 | AGTR1 (0.39) | AGTR1AGTR2 | |
| SCHEMBL8907060 | 0.82 | AGTR1 (0.39) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684029-A | HYPOTENSIVE AGENTS | KARL THOMAE GMBH (DE) | 1997-11-04 | — | — | US | disclosed |