Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8458686 | 1.00 | PIK3CD (0.31) | PIK3CD | |
| SCHEMBL8891955 | 0.88 | PDE4D (0.32) | — | |
| SCHEMBL29224347 | 0.84 | — | — | |
| SCHEMBL10750623 | 0.84 | — | — | |
| SCHEMBL30142081 | 0.78 | ADH1C (0.38) | — | |
| SCHEMBL3821465 | 0.77 | ACACB (0.32) | — | |
| SCHEMBL7453924 | 0.77 | ACACB (0.32) | — | |
| SCHEMBL8925039 | 0.76 | PIK3CD (0.33) | PIK3CD | |
| SCHEMBL737520 | 0.75 | PIK3CD (0.35) | PIK3CD | |
| SCHEMBL29832906 | 0.73 | CHRM1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763041-A1 | INDOLOCARBAZOLE DERIVATIVES FOR SENSITIZING MULTIDRUG-RESISTANT CELLS TO ANTITUMOR AGENTS | Novartis AG (CH) | 1997-03-19 | — | — | EP | claimed |
| WO-1995032975-A1 | INDOLOCARBAZOLE DERIVATIVES FOR SENSITIZING MULTIDRUG-RESISTANT CELLS TO ANTITUMOR AGENTS | CIBA-GEIGY AG (CH) | 1995-12-07 | — | — | WO | claimed |
| EP-0763041-A1 | INDOLOCARBAZOLE DERIVATIVES FOR SENSITIZING MULTIDRUG-RESISTANT CELLS TO ANTITUMOR AGENTS | Novartis AG (CH) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995032975-A1 | INDOLOCARBAZOLE DERIVATIVES FOR SENSITIZING MULTIDRUG-RESISTANT CELLS TO ANTITUMOR AGENTS | CIBA-GEIGY AG (CH) | 1995-12-07 | — | — | WO | disclosed |