Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 1/20 | 0.45 |
| ▸ | EP300 | Q09472 | 6/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | POLG | P54098 | 1/20 | 0.33 |
| ▸ | DCK | P27707 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8900287 | 0.82 | EP300 (0.38) | ALBEP300POLGDCKMEN1 | |
| SCHEMBL8901161 | 0.79 | ALB (0.45) | ALBEP300POLGDCK | |
| SCHEMBL8908488 | 0.79 | LMNA (0.43) | ALBEP300 | |
| SCHEMBL12894756 | 0.74 | ALB (0.43) | ALBEP300POLGDCKKMT2A | |
| SCHEMBL28189199 | 0.70 | ALB (0.45) | ALBEP300POLGDCK | |
| SCHEMBL10171999 | 0.70 | ALB (0.46) | ALBEP300POLGDCK | |
| SCHEMBL10172003 | 0.70 | ALB (0.46) | ALBEP300POLGDCK | |
| SCHEMBL22110738 | 0.68 | ALB (0.50) | ALBEP300POLGDCK | |
| SCHEMBL31611899 | 0.67 | MAPT (0.44) | ALBEP300 | |
| SCHEMBL1226312 | 0.67 | ALB (0.42) | ALBEP300DCKMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997034891-A1 | SUBSTITUTED 1,3-THIAZOLIDINES AND 1,3-THIAZOLIDIN-4-ONES, METHOD FOR PREPARING SAME, AND USE THEREOF AS DRUGS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1997-09-25 | — | — | WO | claimed |
| WO-1997034891-A1 | SUBSTITUTED 1,3-THIAZOLIDINES AND 1,3-THIAZOLIDIN-4-ONES, METHOD FOR PREPARING SAME, AND USE THEREOF AS DRUGS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1997-09-25 | — | — | WO | disclosed |