SCHEMBL8907418

SCHEMBL8907418

N#CC1=CC(=O)C(Cl)=C(Cl)C1=O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.35
BCHE P06276 2/20 0.35
ACHE P22303 2/20 0.35
CES1 P23141 2/20 0.35
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35
ALOX12 P18054 1/20 0.35
MAPK1 P28482 1/20 0.35
RECQL P46063 1/20 0.35
KMT2A Q03164 1/20 0.35
HIF1A Q16665 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3688719 0.83
SCHEMBL28116401 0.83
SCHEMBL28263350 0.72
SCHEMBL1725392 0.72
SCHEMBL4507554 0.70
SCHEMBL9639719 0.68 MEN1 (0.35) CES2BCHEACHECES1KDM4E
Fluoride SCHEMBL27989004 0.68
SCHEMBL744228 0.68 TP53 (0.36) TP53MAPT
SCHEMBL10807066 0.67 GPR84 (0.33) KDM4EMEN1TP53CYP3A4MAPT
SCHEMBL1890738 0.67 MAPT (0.44) CES2BCHEACHECES1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119490551-A Preparation method of dydrogesterone 湖北葛店人福药业有限责任公司 2025-02-21 CN claimed
CN-110483434-A Big birefringence side fluorine benzoxazoles liquid-crystal compounds containing acetylene bond and preparation method thereof UNIV SHAANXI NORMAL 2019-11-22 CN claimed
CN-110483292-A A kind of preparation method of repaglinide key intermediate Hangzhou zhongmei huadong pharmaceutical co ltd 2019-11-22 CN claimed
CN-110483435-A A kind of fluorine-containing benzoxazoles liquid-crystal compounds and its synthetic method of big birefringence UNIV SHAANXI NORMAL 2019-11-22 CN claimed
CN-107082771-B Double alpha-cyano imines substituted isochroman class compounds and its synthetic method 上海大学 2019-11-19 CN claimed
CN-110437846-A Fluorine containing acetylene bond replaces benzoxazoles liquid-crystal compounds and preparation method thereof UNIV SHAANXI NORMAL 2019-11-12 CN claimed
CN-108017682-B A kind of synthetic method of trenbolone acetate 浙江仙居君业药业有限公司 2019-11-08 CN claimed
CN-110240554-A α-thioether aryl acetonitrile compound and its synthetic method 上海大学 2019-09-17 CN claimed
CN-107367495-B A kind of sedimentation type alkaline phosphatase fluorescence probe and its synthetic method and application 湖南大学 2019-09-06 CN claimed
CN-110172078-A The preparation method of 19 hydroxylation cortodoxone derivatives and 19- hydroxyandrostenedione diketone 武汉大学 2019-08-27 CN claimed
CN-105859603-B The preparation method and purposes of prostaglandin analogue 魏威 2018-06-22 CN claimed
CN-105622676-B A kind of ferrocene zinc protoporphyrin compound and its synthesis and the application as dye sensitizing agent 西北师范大学 2018-05-22 CN claimed
CN-108047299-A The preparation method of canrenone important intermediate 广西万德药业有限公司 2018-05-18 CN claimed
CN-108017682-A A kind of synthetic method of trenbolone acetate 浙江仙居君业药业有限公司 2018-05-11 CN claimed
CN-106432315-B A kind of preparation method and application of the Cys fluorescence probes based on fluorine boron pyrroles 湘潭大学 2018-05-08 CN claimed
CN-106083803-B A kind of synthetic method of marine natural products Puupehedione 威海惠安康生物科技有限公司 2018-05-04 CN claimed
EP-0606453-B1 PHOTOVOLTAIC CELL ASULAB SA (CH) 1997-06-04 EP claimed
US-5482570-A Photovoltaic cell ASULAB S.A. (CH) 1996-01-09 US claimed
EP-0606453-A1 PHOTOVOLTAIC CELL. ASULAB SA (CH) 1994-07-20 EP claimed
WO-1994003930-A1 PHOTOVOLTAIC CELL ASULAB S.A. (CH) 1994-02-17 WO claimed