Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 5/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA5A | P35218 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20483621 | 1.00 | TSHR (0.58) | TSHRCYP2D6ALDH1A1MAPK1LMNA | |
| SCHEMBL8722654 | 0.90 | TSHR (0.64) | TSHRCYP2D6ALDH1A1MAPK1LMNA | |
| SCHEMBL10359936 | 0.90 | TSHR (0.64) | TSHRCYP2D6ALDH1A1MAPK1LMNA | |
| SCHEMBL8722653 | 0.90 | TSHR (0.64) | TSHRCYP2D6ALDH1A1MAPK1LMNA | |
| SCHEMBL15514610 | 0.90 | TSHR (0.64) | TSHRCYP2D6ALDH1A1MAPK1LMNA | |
| SCHEMBL23742930 | 0.90 | TSHR (0.64) | TSHRCYP2D6ALDH1A1MAPK1LMNA | |
| SCHEMBL15919152 | 0.89 | LMNA (0.55) | TSHRCYP2D6ALDH1A1MAPK1LMNA | |
| SCHEMBL6859193 | 0.89 | LMNA (0.62) | TSHRCYP2D6ALDH1A1MAPK1LMNA | |
| SCHEMBL6867867 | 0.89 | LMNA (0.62) | TSHRCYP2D6ALDH1A1MAPK1LMNA | |
| SCHEMBL15919148 | 0.88 | LMNA (0.72) | TSHRCYP2D6ALDH1A1MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656721-A | HAVING SUGAR MOIETY; PROLONGED DURATION OF ACTION | SANDOZ LTD. (CH) | 1997-08-12 | — | — | US | disclosed |