SCHEMBL8907571

SCHEMBL8907571

Cc1ccc(C(C)(NC(=O)c2cccc(Cl)c2)C(=O)O)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
ALDH1A1 P00352 1/20 0.48
KCNK3 O14649 2/20 0.48
KCNK9 Q9NPC2 2/20 0.48
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
CASP3 P42574 1/20 0.46
SENP8 Q96LD8 1/20 0.46
SENP7 Q9BQF6 1/20 0.46
SENP6 Q9GZR1 1/20 0.46
S1PR1 P21453 1/20 0.46
S1PR3 Q99500 1/20 0.46
S1PR5 Q9H228 1/20 0.46
LMNA P02545 1/20 0.45
KMT2A Q03164 1/20 0.45
GPR132 Q9UNW8 1/20 0.45
P2RY14 Q15391 1/20 0.43
PKM P14618 1/20 0.43
KCNQ3 O43525 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28250847 0.86 NPC1 (0.53) MAPTSMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL28531213 0.85 NPC1 (0.50) KCNK3KCNK9NPC1RAB9AGPR132
SCHEMBL8907719 0.84 MAPT (0.53) MAPTSMN1; SMN2ALDH1A1KCNK3KCNK9
SCHEMBL28528461 0.82 POLB (0.50) MAPTSMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL28451351 0.79 KCNK3 (0.53) MAPTSMN1; SMN2ALDH1A1KCNK3KCNK9
SCHEMBL28250190 0.78 POLB (0.54) SMN1; SMN2ALDH1A1KCNK9NPC1RAB9A
SCHEMBL28908852 0.77 POLB (0.53) MAPTSMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL8396092 0.77 SLC6A2 (0.58) SMN1; SMN2ALDH1A1KCNK3KCNK9LMNA
SCHEMBL3046746 0.76 VNN1 (0.57) MAPTALDH1A1KCNK3KCNK9NPC1
SCHEMBL28536704 0.74 CTDSP1 (0.53) MAPTSMN1; SMN2NPC1RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5691278-A HERBICIDES KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 1997-11-25 US disclosed