Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907920 | 1.00 | CA2 (0.33) | CA2 | |
| SCHEMBL8906698 | 0.95 | CA2 (0.30) | CA2 | |
| SCHEMBL8906695 | 0.95 | CA2 (0.30) | CA2 | |
| SCHEMBL6137309 | 0.87 | CA2 (0.37) | CA2 | |
| SCHEMBL6137393 | 0.87 | CA2 (0.37) | CA2 | |
| SCHEMBL1057130 | 0.87 | CA2 (0.37) | CA2 | |
| SCHEMBL1057409 | 0.82 | CA2 (0.34) | CA2 | |
| SCHEMBL9794366 | 0.82 | CA2 (0.34) | CA2 | |
| SCHEMBL6137558 | 0.82 | CA2 (0.34) | CA2 | |
| SCHEMBL9794153 | 0.81 | CA2 (0.33) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639899-A | TREATMENT OF PERIPHERAL CIRCULATORY DISTURBANCES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1997-06-17 | — | — | US | disclosed |
| US-5583158-A | ANTICOAGULANTS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1996-12-10 | — | — | US | disclosed |
| EP-0597095-B1 | PROSTAGLANDIN E1 ANALOGUE | TAISHO PHARMACEUTICAL CO LTD (JP) | 1996-10-30 | — | — | EP | disclosed |
| US-5449815-A | Prostaglandin E1 analogues | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1995-09-12 | — | — | US | disclosed |
| EP-0666257-A1 | PROSTAGLANDIN E 1? ANALOG | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1995-08-09 | — | — | EP | disclosed |
| EP-0597095-A1 | PROSTAGLANDIN E1 ANALOGUE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1994-05-18 | — | — | EP | disclosed |
| EP-0591532-A1 | PROSTAGLANDIN E 1? ANALOGUE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1994-04-13 | — | — | EP | disclosed |
| EP-0255098-B1 | Novel 8-(lower alkyl) bicyclo [4.2.0] octane derivatives with valuable therapeutic properties | SYNTEX (U.S.A.) INC. (US) | 1991-05-29 | — | — | EP | disclosed |
| US-4983627-A | Treating atherosclerosis, thrombosis and vasospasms; anticholesterol,-secretory,-ulcer and hypotensive agents | SYNTEX (U.S.A.) INC. (US) | 1991-01-08 | — | — | US | disclosed |
| EP-0196617-B1 | [4.2.0]bicyclooctane derivatives, process for their preparation and pharmaceutical compositions containing same | SYNTEX (U.S.A.) INC. (US) | 1989-05-31 | — | — | EP | disclosed |
| US-4735966-A | ANTICOAGULANTS, VASODILATORS, HYPOTENSIVE AND ANTICHOLESTEROL AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-04-05 | — | — | US | disclosed |
| EP-0257609-A2 | Novel substituted (4.2.0)Bicyclooctane derivatives with valuable therapeutic properties | SYNTEX (U.S.A.) INC. (US) | 1988-03-02 | — | — | EP | disclosed |
| EP-0255098-A1 | Novel 8-(lower alkyl) bicyclo [4.2.0] octane derivatives with valuable therapeutic properties | SYNTEX (U.S.A.) INC. (US) | 1988-02-03 | — | — | EP | disclosed |
| US-4678805-A | Novel 8-(lower alkyl)bicyclo[4.2.0]octane derivatives with valuable therapeutic properties | SYNTEX (U.S.A.) INC. (US) | 1987-07-07 | — | — | US | disclosed |
| EP-0196617-A1 | [4.2.0]bicyclooctane derivatives, process for their preparation and pharmaceutical compositions containing same | SYNTEX (U.S.A.) INC. (US) | 1986-10-08 | — | — | EP | disclosed |
| US-4608388-A | Novel [4,2,0]bicyclooctane derivatives with valuable therapeutic properties | SYNTEX (U.S.A.) INC. (US) | 1986-08-26 | — | — | US | disclosed |