Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | PRKDC | P78527 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | FDPS | P14324 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8908142 | 1.00 | ALDH1A1 (0.60) | ALDH1A1KDM4ETDP1MAPTCYP3A4 | |
| SCHEMBL16373807 | 0.92 | ALDH1A1 (0.53) | ALDH1A1KDM4ETDP1MAPTCYP3A4 | |
| SCHEMBL6318854 | 0.91 | ALDH1A1 (0.60) | ALDH1A1KDM4ETDP1MAPTCYP3A4 | |
| SCHEMBL6318850 | 0.91 | ALDH1A1 (0.60) | ALDH1A1KDM4ETDP1MAPTCYP3A4 | |
| SCHEMBL3173753 | 0.90 | ALDH1A1 (0.50) | ALDH1A1KDM4ETDP1MAPTCYP3A4 | |
| SCHEMBL3173742 | 0.90 | ALDH1A1 (0.50) | ALDH1A1KDM4ETDP1MAPTCYP3A4 | |
| SCHEMBL16333817 | 0.87 | ALDH1A1 (0.60) | ALDH1A1KDM4ETDP1MAPTCYP3A4 | |
| SCHEMBL16333816 | 0.87 | ALDH1A1 (0.60) | ALDH1A1KDM4ETDP1MAPTCYP3A4 | |
| SCHEMBL17980698 | 0.83 | MAPT (0.54) | ALDH1A1MAPTRAB9ASTAT3BACE1 | |
| SCHEMBL29493914 | 0.83 | MAPT (0.54) | ALDH1A1MAPTRAB9ASTAT3BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670664-A | Photosensitive organic compounds that release carbon monoxide upon illumination | UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE (US) | 1997-09-23 | — | — | US | disclosed |