Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2268476 | 0.76 | TSHR (0.32) | TSHRTDP1 | |
| SCHEMBL2276810 | 0.73 | EPHX1 (0.37) | — | |
| SCHEMBL2275406 | 0.70 | SIGMAR1 (0.33) | — | |
| SCHEMBL523017 | 0.67 | — | — | |
| SCHEMBL4524059 | 0.65 | TSHR (0.40) | TSHRALDH1A1TDP1 | |
| SCHEMBL4528581 | 0.65 | TSHR (0.40) | TSHRALDH1A1TDP1 | |
| SCHEMBL4517659 | 0.65 | TSHR (0.40) | TSHRALDH1A1TDP1 | |
| SCHEMBL4526516 | 0.65 | TSHR (0.40) | TSHRALDH1A1TDP1 | |
| SCHEMBL4536124 | 0.65 | TSHR (0.40) | TSHRALDH1A1TDP1 | |
| SCHEMBL4536407 | 0.65 | TSHR (0.40) | TSHRALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624680-A | SKIN ABSORPTION OF DRUGS WITH POLYETHERSILOXANE BLOCK COPOLYMERS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1997-04-29 | — | — | US | disclosed |
| EP-0710688-A1 | HYDROXYSILYL-TERMINATED POLYOXYETHYLENE COMPOUND, QUATERNARY-SALT-TERMINATED BLOCK COPOLYMER, AND PERCUTANEOUS ABSORPTION PROMOTER | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1996-05-08 | — | — | EP | disclosed |