Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4154463 | 0.85 | KDM4E (0.38) | KDM4ECYP1A2SMN1; SMN2ADRA2BMAPK1 | |
| SCHEMBL4886778 | 0.83 | KDM4E (0.46) | KDM4ECYP1A2SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL2183758 | 0.79 | MCL1 (0.49) | KDM4ELMNA | |
| SCHEMBL6671002 | 0.79 | TOP1 (0.47) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL4884272 | 0.78 | KDM4E (0.36) | KDM4ECYP1A2ADRA2BMAPK1ALDH1A1 | |
| SCHEMBL10330763 | 0.77 | KDM4E (0.47) | KDM4ECYP1A2SMN1; SMN2ADRA2BMAPK1 | |
| SCHEMBL4887129 | 0.76 | KDM4E (0.44) | KDM4ESMN1; SMN2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL4717957 | 0.74 | KDM4E (0.63) | KDM4ECYP1A2SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL29433778 | 0.74 | KDM4E (0.63) | KDM4ECYP1A2SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL4717954 | 0.74 | KDM4E (0.63) | KDM4ECYP1A2SMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58225092-A | — | — | None | — | — | JP | disclosed |
| US-5663411-A | (+)2-benzoyl-3-[(prop-2(S)-yl)amino]acrylate derivatives and a method for the preparation of the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1997-09-02 | — | — | US | disclosed |
| US-5539110-A | Method for the preparation of (-)piperazine benzoxazine derivatives | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1996-07-23 | — | — | US | disclosed |
| US-5516926-A | (+) 2-benzoyl-3-(silyloxyprop-2(S)-yl)aminoacrylate derivatives and a method for preparing the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1996-05-14 | — | — | US | disclosed |
| EP-0394553-B1 | Use of fluorine containing pyridone carboxylic acid derivatives for preparing a medicament for the treatment of HIV infections | DAIICHI SEIYAKU CO (JP) | 1995-06-21 | — | — | EP | disclosed |
| EP-0470252-A1 | ANTI-HIV DRUG | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1992-02-12 | — | — | EP | disclosed |
| JP-S58225092-A | PYRIDO(1,2,3-DE)(1,4)BENZOXAZINE-6-CARBOXYLIC ACID DERIVATIVE | DAI ICHI SEIYAKU CO LTD | 1983-12-27 | — | — | JP | disclosed |